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In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip.
J Cell Sci. 2021 Sep 15;134(18):jcs259010. doi: 10.1242/jcs.259010. Epub 2021 Sep 23.
J Cell Sci. 2021.
PMID: 34415027
Free PMC article.
IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.
Wingfield JL, Mengoni I, Bomberger H, Jiang YY, Walsh JD, Brown JM, Picariello T, Cochran DA, Zhu B, Pan J, Eggenschwiler J, Gaertig J, Witman GB, Kner P, Lechtreck K.
Wingfield JL, et al. Among authors: mengoni i.
Elife. 2017 May 31;6:e26609. doi: 10.7554/eLife.26609.
Elife. 2017.
PMID: 28562242
Free PMC article.
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In vivo analyses of radial spoke transport, assembly, repair and maintenance.
Lechtreck KF, Mengoni I, Okivie B, Hilderhoff KB.
Lechtreck KF, et al. Among authors: mengoni i.
Cytoskeleton (Hoboken). 2018 Aug;75(8):352-362. doi: 10.1002/cm.21457. Epub 2018 Sep 10.
Cytoskeleton (Hoboken). 2018.
PMID: 30070024
Free PMC article.
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Copper-zinc superoxide dismutase (SOD1) is released by microglial cells and confers neuroprotection against 6-OHDA neurotoxicity.
Polazzi E, Mengoni I, Caprini M, Peña-Altamira E, Kurtys E, Monti B.
Polazzi E, et al. Among authors: mengoni i.
Neurosignals. 2013;21(1-2):112-28. doi: 10.1159/000337115. Epub 2012 May 9.
Neurosignals. 2013.
PMID: 22572742
Free article.
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Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology.
Polazzi E, Mengoni I, Peña-Altamira E, Massenzio F, Virgili M, Petralla S, Monti B.
Polazzi E, et al. Among authors: mengoni i.
J Neuropathol Exp Neurol. 2015 Aug;74(8):818-34. doi: 10.1097/NEN.0000000000000222.
J Neuropathol Exp Neurol. 2015.
PMID: 26185969
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Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose.
Massenzio F, Peña-Altamira E, Petralla S, Virgili M, Zuccheri G, Miti A, Polazzi E, Mengoni I, Piffaretti D, Monti B.
Massenzio F, et al. Among authors: mengoni i.
Biochim Biophys Acta Mol Basis Dis. 2018 Dec;1864(12):3771-3785. doi: 10.1016/j.bbadis.2018.10.013. Epub 2018 Oct 10.
Biochim Biophys Acta Mol Basis Dis. 2018.
PMID: 30315929
Free article.
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Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors.
Peña-Altamira LE, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, Poli A, Zuccarini M, Ciccarelli R, Di Iorio P, Virgili M, Monti B, Caciagli F.
Peña-Altamira LE, et al. Among authors: mengoni i.
Neurochem Int. 2018 May;115:37-49. doi: 10.1016/j.neuint.2017.10.010. Epub 2017 Oct 20.
Neurochem Int. 2018.
PMID: 29061383
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