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The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels.
Axelsson E, Ljungvall I, Bhoumik P, Conn LB, Muren E, Ohlsson Å, Olsen LH, Engdahl K, Hagman R, Hanson J, Kryvokhyzha D, Pettersson M, Grenet O, Moggs J, Del Rio-Espinola A, Epe C, Taillon B, Tawari N, Mane S, Hawkins T, Hedhammar Å, Gruet P, Häggström J, Lindblad-Toh K. Axelsson E, et al. Among authors: moggs j. PLoS Genet. 2021 Sep 2;17(9):e1009726. doi: 10.1371/journal.pgen.1009726. eCollection 2021 Sep. PLoS Genet. 2021. PMID: 34473707 Free PMC article.
Translational Safety Genetics.
Bhoumik P, Del Rio-Espinola A, Hahne F, Moggs J, Grenet O. Bhoumik P, et al. Among authors: moggs j. Toxicol Pathol. 2017 Jan;45(1):119-126. doi: 10.1177/0192623316675064. Epub 2016 Dec 8. Toxicol Pathol. 2017. PMID: 27932582 Review.
Correction: The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels.
Axelsson E, Ljungvall I, Bhoumik P, Conn LB, Muren E, Ohlsson Å, Olsen LH, Engdahl K, Hagman R, Hanson J, Kryvokhyzha D, Pettersson M, Grenet O, Moggs J, Rio-Espinola AD, Epe C, Taillon B, Tawari N, Mane S, Hawkins T, Hedhammar Å, Gruet P, Häggström J, Lindblad-Toh K. Axelsson E, et al. Among authors: moggs j. PLoS Genet. 2022 Jan 27;18(1):e1010039. doi: 10.1371/journal.pgen.1010039. eCollection 2022 Jan. PLoS Genet. 2022. PMID: 35085237 Free PMC article.
Heart structure-specific transcriptomic atlas reveals conserved microRNA-mRNA interactions.
Vacchi-Suzzi C, Hahne F, Scheubel P, Marcellin M, Dubost V, Westphal M, Boeglen C, Büchmann-Møller S, Cheung MS, Cordier A, De Benedetto C, Deurinck M, Frei M, Moulin P, Oakeley E, Grenet O, Grevot A, Stull R, Theil D, Moggs JG, Marrer E, Couttet P. Vacchi-Suzzi C, et al. PLoS One. 2013;8(1):e52442. doi: 10.1371/journal.pone.0052442. Epub 2013 Jan 2. PLoS One. 2013. PMID: 23300973 Free PMC article.
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.
Lempiäinen H, Müller A, Brasa S, Teo SS, Roloff TC, Morawiec L, Zamurovic N, Vicart A, Funhoff E, Couttet P, Schübeler D, Grenet O, Marlowe J, Moggs J, Terranova R. Lempiäinen H, et al. Among authors: moggs j. PLoS One. 2011 Mar 24;6(3):e18216. doi: 10.1371/journal.pone.0018216. PLoS One. 2011. PMID: 21455306 Free PMC article.
Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome.
Brasa S, Mueller A, Jacquemont S, Hahne F, Rozenberg I, Peters T, He Y, McCormack C, Gasparini F, Chibout SD, Grenet O, Moggs J, Gomez-Mancilla B, Terranova R. Brasa S, et al. Among authors: moggs j. Clin Epigenetics. 2016 Feb 5;8:15. doi: 10.1186/s13148-016-0181-x. eCollection 2016. Clin Epigenetics. 2016. PMID: 26855684 Free PMC article.
Using human genetics to improve safety assessment of therapeutics.
Carss KJ, Deaton AM, Del Rio-Espinola A, Diogo D, Fielden M, Kulkarni DA, Moggs J, Newham P, Nelson MR, Sistare FD, Ward LD, Yuan J. Carss KJ, et al. Among authors: moggs j. Nat Rev Drug Discov. 2023 Feb;22(2):145-162. doi: 10.1038/s41573-022-00561-w. Epub 2022 Oct 19. Nat Rev Drug Discov. 2023. PMID: 36261593 Review.
Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.
Lempiäinen H, Couttet P, Bolognani F, Müller A, Dubost V, Luisier R, Del Rio Espinola A, Vitry V, Unterberger EB, Thomson JP, Treindl F, Metzger U, Wrzodek C, Hahne F, Zollinger T, Brasa S, Kalteis M, Marcellin M, Giudicelli F, Braeuning A, Morawiec L, Zamurovic N, Längle U, Scheer N, Schübeler D, Goodman J, Chibout SD, Marlowe J, Theil D, Heard DJ, Grenet O, Zell A, Templin MF, Meehan RR, Wolf RC, Elcombe CR, Schwarz M, Moulin P, Terranova R, Moggs JG. Lempiäinen H, et al. Among authors: moggs jg. Toxicol Sci. 2013 Feb;131(2):375-86. doi: 10.1093/toxsci/kfs303. Epub 2012 Oct 22. Toxicol Sci. 2013. PMID: 23091169
Perturbation of microRNAs in rat heart during chronic doxorubicin treatment.
Vacchi-Suzzi C, Bauer Y, Berridge BR, Bongiovanni S, Gerrish K, Hamadeh HK, Letzkus M, Lyon J, Moggs J, Paules RS, Pognan F, Staedtler F, Vidgeon-Hart MP, Grenet O, Couttet P. Vacchi-Suzzi C, et al. Among authors: moggs j. PLoS One. 2012;7(7):e40395. doi: 10.1371/journal.pone.0040395. Epub 2012 Jul 31. PLoS One. 2012. PMID: 22859947 Free PMC article.
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion.
Vitobello A, Perner J, Beil J, Zhu J, Del Río-Espínola A, Morawiec L, Westphal M, Dubost V, Altorfer M, Naumann U, Mueller A, Kapur K, Borowsky M, Henderson C, Wolf CR, Schwarz M, Moggs J, Terranova R. Vitobello A, et al. Among authors: moggs j. Life Sci Alliance. 2019 Oct 15;2(5):e201900461. doi: 10.26508/lsa.201900461. Print 2019 Oct. Life Sci Alliance. 2019. PMID: 31615920 Free PMC article.
80 results