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Page 1
CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes.
Kosaka A, Ishibashi K, Nagato T, Kitamura H, Fujiwara Y, Yasuda S, Nagata M, Harabuchi S, Hayashi R, Yajima Y, Ohara K, Kumai T, Aoki N, Komohara Y, Oikawa K, Harabuchi Y, Kitada M, Kobayashi H, Ohkuri T. Kosaka A, et al. Among authors: oikawa k. J Exp Med. 2021 Nov 1;218(11):e20200792. doi: 10.1084/jem.20200792. Epub 2021 Sep 24. J Exp Med. 2021. PMID: 34559187 Free PMC article.
Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site.
Ohkuri T, Kosaka A, Ishibashi K, Kumai T, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Celis E, Kobayashi H. Ohkuri T, et al. Among authors: oikawa k. Cancer Immunol Immunother. 2017 Jun;66(6):705-716. doi: 10.1007/s00262-017-1975-1. Epub 2017 Feb 27. Cancer Immunol Immunother. 2017. PMID: 28243692 Free PMC article.
Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.
Uehara J, Ohkuri T, Kosaka A, Ishibashi K, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Ishida-Yamamoto A, Kobayashi H. Uehara J, et al. Among authors: oikawa k. Biochem Biophys Res Commun. 2017 Aug 19;490(2):521-527. doi: 10.1016/j.bbrc.2017.06.072. Epub 2017 Jun 15. Biochem Biophys Res Commun. 2017. PMID: 28624449
PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma.
Hirata-Nozaki Y, Ohkuri T, Ohara K, Kumai T, Nagata M, Harabuchi S, Kosaka A, Nagato T, Ishibashi K, Oikawa K, Aoki N, Ohara M, Harabuchi Y, Uno Y, Takei H, Celis E, Kobayashi H. Hirata-Nozaki Y, et al. Among authors: oikawa k. J Transl Med. 2019 Jun 20;17(1):207. doi: 10.1186/s12967-019-1957-5. J Transl Med. 2019. PMID: 31221178 Free PMC article.
Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma.
Harabuchi S, Kosaka A, Yajima Y, Nagata M, Hayashi R, Kumai T, Ohara K, Nagato T, Oikawa K, Ohara M, Harabuchi Y, Ohkuri T, Kobayashi H. Harabuchi S, et al. Among authors: oikawa k. Biochem Biophys Res Commun. 2020 Feb 5;522(2):408-414. doi: 10.1016/j.bbrc.2019.11.107. Epub 2019 Nov 23. Biochem Biophys Res Commun. 2020. PMID: 31771883
A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment.
Nagata M, Kosaka A, Yajima Y, Yasuda S, Ohara M, Ohara K, Harabuchi S, Hayashi R, Funakoshi H, Ueda J, Kumai T, Nagato T, Oikawa K, Harabuchi Y, Esteban C, Ohkuri T, Kobayashi H. Nagata M, et al. Among authors: oikawa k. Cancer Immunol Immunother. 2021 Aug;70(8):2301-2312. doi: 10.1007/s00262-021-02864-0. Epub 2021 Jan 28. Cancer Immunol Immunother. 2021. PMID: 33507344 Free PMC article.
Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy.
Ishibashi K, Kumai T, Ohkuri T, Kosaka A, Nagato T, Hirata Y, Ohara K, Oikawa K, Aoki N, Akiyama N, Sado M, Kitada M, Harabuchi Y, Celis E, Kobayashi H. Ishibashi K, et al. Among authors: oikawa k. Oncoimmunology. 2016 Mar 30;5(6):e1169356. doi: 10.1080/2162402X.2016.1169356. eCollection 2016 Jun. Oncoimmunology. 2016. PMID: 27471649 Free PMC article.
539 results