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Spatiotemporal Correlation Spectroscopy Reveals a Protective Effect of Peptide-Based GLP-1 Receptor Agonism against Lipotoxicity on Insulin Granule Dynamics in Primary Human β-Cells.
Ferri G, Tesi M, Pesce L, Bugliani M, Grano F, Occhipinti M, Suleiman M, De Luca C, Marselli L, Marchetti P, Cardarelli F. Ferri G, et al. Among authors: marselli l. Pharmaceutics. 2021 Sep 3;13(9):1403. doi: 10.3390/pharmaceutics13091403. Pharmaceutics. 2021. PMID: 34575477 Free PMC article.
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patané G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P. Lupi R, et al. Among authors: marselli l. Diabetes. 2002 May;51(5):1437-42. doi: 10.2337/diabetes.51.5.1437. Diabetes. 2002. PMID: 11978640
Goals of treatment for type 2 diabetes: beta-cell preservation for glycemic control.
Marchetti P, Lupi R, Del Guerra S, Bugliani M, D'Aleo V, Occhipinti M, Boggi U, Marselli L, Masini M. Marchetti P, et al. Among authors: marselli l. Diabetes Care. 2009 Nov;32 Suppl 2(Suppl 2):S178-83. doi: 10.2337/dc09-S306. Diabetes Care. 2009. PMID: 19875548 Free PMC article. Review. No abstract available.
161 results