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Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787.
Hirst DJ, Bamborough P, Al-Mahdi N, Angell DC, Barnett HA, Baxter A, Bit RA, Brown JA, Chung CW, Craggs PD, Davis RP, Demont EH, Ferrie A, Gordon LJ, Harada I, Ho TCT, Holyer ID, Hooper-Greenhill E, Jones KL, Lindon MJ, Lovatt C, Lugo D, Maller C, McGonagle G, Messenger C, Mitchell DJ, Pascoe DD, Patel VK, Patten C, Poole DL, Shah RR, Rioja I, Stafford KAJ, Tape D, Taylor S, Theodoulou NH, Tomlinson L, Wall ID, Wellaway CR, White G, Prinjha RK, Humphreys PG. Hirst DJ, et al. Among authors: mitchell dj. J Med Chem. 2024 Jun 12. doi: 10.1021/acs.jmedchem.4c00959. Online ahead of print. J Med Chem. 2024. PMID: 38866424
Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline.
Demay MB, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M, Lips P, Mitchell DM, Murad MH, Powers S, Rao SD, Scragg R, Tayek JA, Valent AM, Walsh JME, McCartney CR. Demay MB, et al. Among authors: mitchell dm. J Clin Endocrinol Metab. 2024 Jun 3:dgae290. doi: 10.1210/clinem/dgae290. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38828931
Heatwave attribution based on reliable operational weather forecasts.
Leach NJ, Roberts CD, Aengenheyster M, Heathcote D, Mitchell DM, Thompson V, Palmer T, Weisheimer A, Allen MR. Leach NJ, et al. Among authors: mitchell dm. Nat Commun. 2024 May 30;15(1):4530. doi: 10.1038/s41467-024-48280-7. Nat Commun. 2024. PMID: 38816393 Free PMC article.
4,349 results