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Antipruritic Effects of Kappa Opioid Receptor Agonists: Evidence from Rodents to Humans.
Inan S, Cowan A. Inan S, et al. Among authors: cowan a. Handb Exp Pharmacol. 2022;271:275-292. doi: 10.1007/164_2020_420. Handb Exp Pharmacol. 2022. PMID: 33296031
These behaviors were blocked by early benzomorphan kappa opioid receptor (KOR) agonists as reported by Gmerek and Cowan in 1984. This was the first evidence that KORs may be involved in the sensation of itch-like behaviors. Subsequent development of additional animal model …
These behaviors were blocked by early benzomorphan kappa opioid receptor (KOR) agonists as reported by Gmerek and Cowan in 1984. This …
779 results