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Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Chong KY, Kang M, Garofalo F, Ueno D, Liang H, Cady S, Madarikan O, Pitruzzello N, Tsai CH, Hartwich TMP, Shuch BM, Yang-Hartwich Y. Chong KY, et al. Mol Pharmacol. 2019 Aug;96(2):168-179. doi: 10.1124/mol.119.116137. Epub 2019 Jun 7. Mol Pharmacol. 2019. PMID: 31175180
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice.
Kim O, Park EY, Klinkebiel DL, Pack SD, Shin YH, Abdullaev Z, Emerson RE, Coffey DM, Kwon SY, Creighton CJ, Kwon S, Chang EC, Chiang T, Yatsenko AN, Chien J, Cheon DJ, Yang-Hartwich Y, Nakshatri H, Nephew KP, Behringer RR, Fernández FM, Cho CH, Vanderhyden B, Drapkin R, Bast RC Jr, Miller KD, Karpf AR, Kim J. Kim O, et al. PLoS Genet. 2020 Jun 4;16(6):e1008808. doi: 10.1371/journal.pgen.1008808. eCollection 2020 Jun. PLoS Genet. 2020. PMID: 32497036 Free PMC article.
Homologous recombination deficiency (HRD) signature-3 in ovarian and uterine carcinosarcomas correlates with preclinical sensitivity to Olaparib, a poly (adenosine diphosphate [ADP]- ribose) polymerase (PARP) inhibitor.
Tymon-Rosario JR, Manara P, Manavella DD, Bellone S, Hartwich TMP, Harold J, Yang-Hartwich Y, Zipponi M, Choi J, Jeong K, Mutlu L, Yang K, Altwerger G, Menderes G, Ratner E, Huang GS, Clark M, Andikyan V, Azodi M, Schwartz PE, Alexandrov LB, Santin AD. Tymon-Rosario JR, et al. Gynecol Oncol. 2022 Jul;166(1):117-125. doi: 10.1016/j.ygyno.2022.05.005. Epub 2022 May 20. Gynecol Oncol. 2022. PMID: 35599167
34 results