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Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT.
Inoue T, Koyama M, Kaida K, Ikegame K, Ensbey KS, Samson L, Takahashi S, Zhang P, Minnie SA, Maruyama S, Ishii S, Daimon T, Fukuda T, Nakamae H, Ara T, Maruyama Y, Ishiyama K, Ichinohe T, Atsuta Y, Blazar BR, Furlan SN, Ogawa H, Hill GR. Inoue T, et al. Among authors: hill gr. JCI Insight. 2021 Nov 22;6(22):e153551. doi: 10.1172/jci.insight.153551. JCI Insight. 2021. PMID: 34637399 Free PMC article.
Type I-IFNs control GVHD and GVL responses after transplantation.
Robb RJ, Kreijveld E, Kuns RD, Wilson YA, Olver SD, Don AL, Raffelt NC, De Weerd NA, Lineburg KE, Varelias A, Markey KA, Koyama M, Clouston AD, Hertzog PJ, Macdonald KP, Hill GR. Robb RJ, et al. Among authors: hill gr. Blood. 2011 Sep 22;118(12):3399-409. doi: 10.1182/blood-2010-12-325746. Epub 2011 Jun 30. Blood. 2011. PMID: 21719602 Free article.
Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets.
Markey KA, Koyama M, Kuns RD, Lineburg KE, Wilson YA, Olver SD, Raffelt NC, Don AL, Varelias A, Robb RJ, Cheong M, Engwerda CR, Steptoe RJ, Ramshaw HS, Lopez AF, Vega-Ramos J, Lew AM, Villadangos JA, Hill GR, MacDonald KP. Markey KA, et al. Among authors: hill gr. Blood. 2012 Jun 14;119(24):5918-30. doi: 10.1182/blood-2011-12-398164. Epub 2012 Mar 13. Blood. 2012. PMID: 22415754 Free article.
Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
Robb RJ, Lineburg KE, Kuns RD, Wilson YA, Raffelt NC, Olver SD, Varelias A, Alexander KA, Teal BE, Sparwasser T, Hammerling GJ, Markey KA, Koyama M, Clouston AD, Engwerda CR, Hill GR, MacDonald KP. Robb RJ, et al. Among authors: hill gr. Blood. 2012 Jun 14;119(24):5898-908. doi: 10.1182/blood-2011-12-396119. Epub 2012 Apr 26. Blood. 2012. PMID: 22538855 Free article.
Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo.
Zhang P, Tey SK, Koyama M, Kuns RD, Olver SD, Lineburg KE, Lor M, Teal BE, Raffelt NC, Raju J, Leveque L, Markey KA, Varelias A, Clouston AD, Lane SW, MacDonald KP, Hill GR. Zhang P, et al. Among authors: hill gr. J Immunol. 2013 Nov 15;191(10):5291-303. doi: 10.4049/jimmunol.1301181. Epub 2013 Oct 11. J Immunol. 2013. PMID: 24123683
Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans.
Flynn R, Du J, Veenstra RG, Reichenbach DK, Panoskaltsis-Mortari A, Taylor PA, Freeman GJ, Serody JS, Murphy WJ, Munn DH, Sarantopoulos S, Luznik L, Maillard I, Koreth J, Cutler C, Soiffer RJ, Antin JH, Ritz J, Dubovsky JA, Byrd JC, MacDonald KP, Hill GR, Blazar BR. Flynn R, et al. Among authors: hill gr. Blood. 2014 Jun 19;123(25):3988-98. doi: 10.1182/blood-2014-03-562231. Epub 2014 May 12. Blood. 2014. PMID: 24820310 Free PMC article.
278 results