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Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport.
Spieth L, Berghoff SA, Stumpf SK, Winchenbach J, Michaelis T, Watanabe T, Gerndt N, Düking T, Hofer S, Ruhwedel T, Shaib AH, Willig K, Kronenberg K, Karst U, Frahm J, Rhee JS, Minguet S, Möbius W, Kruse N, von der Brelie C, Michels P, Stadelmann C, Hülper P, Saher G. Spieth L, et al. Among authors: minguet s. Neurooncol Adv. 2021 Sep 20;3(1):vdab140. doi: 10.1093/noajnl/vdab140. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34647026 Free PMC article.
MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production.
Langenbach M, Giesler S, Richtsfeld S, Costa-Pereira S, Rindlisbacher L, Wertheimer T, Braun LM, Andrieux G, Duquesne S, Pfeifer D, Woessner NM, Menssen HD, Taromi S, Duyster J, Börries M, Brummer T, Blazar BR, Minguet S, Turko P, Levesque MP, Becher B, Zeiser R. Langenbach M, et al. Among authors: minguet s. Mol Cancer Res. 2023 Aug 1;21(8):849-864. doi: 10.1158/1541-7786.MCR-22-0898. Mol Cancer Res. 2023. PMID: 37071397 Free PMC article.
Enhanced B-cell activation mediated by TLR4 and BCR crosstalk.
Minguet S, Dopfer EP, Pollmer C, Freudenberg MA, Galanos C, Reth M, Huber M, Schamel WW. Minguet S, et al. Eur J Immunol. 2008 Sep;38(9):2475-87. doi: 10.1002/eji.200738094. Eur J Immunol. 2008. PMID: 18819072 Free article.
Activation of the TCR complex by peptide-MHC and superantigens.
Louis-Dit-Sully C, Blumenthal B, Duchniewicz M, Beck-Garcia K, Fiala GJ, Beck-García E, Mukenhirn M, Minguet S, Schamel WW. Louis-Dit-Sully C, et al. Among authors: minguet s. Exp Suppl. 2014;104:9-23. doi: 10.1007/978-3-0348-0726-5_2. Exp Suppl. 2014. PMID: 24214615 Review.
The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.
Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA. Dopfer EP, et al. Among authors: minguet s. Cell Rep. 2014 Jun 12;7(5):1704-1715. doi: 10.1016/j.celrep.2014.04.049. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857663 Free article.
Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells.
Schönle A, Hartl FA, Mentzel J, Nöltner T, Rauch KS, Prestipino A, Wohlfeil SA, Apostolova P, Hechinger AK, Melchinger W, Fehrenbach K, Guadamillas MC, Follo M, Prinz G, Ruess AK, Pfeifer D, del Pozo MA, Schmitt-Graeff A, Duyster J, Hippen KI, Blazar BR, Schachtrup K, Minguet S, Zeiser R. Schönle A, et al. Among authors: minguet s. Blood. 2016 Apr 14;127(15):1930-9. doi: 10.1182/blood-2015-09-672428. Epub 2016 Feb 2. Blood. 2016. PMID: 26837700 Free PMC article.
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