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Ragulator-Rag and ROS TORment gasdermin D pore formation.
Magupalli VG, Fontana P, Wu H. Magupalli VG, et al. Among authors: wu h. Trends Immunol. 2021 Nov;42(11):948-950. doi: 10.1016/j.it.2021.09.014. Epub 2021 Oct 15. Trends Immunol. 2021. PMID: 34663551 Free PMC article.
Cryo-EM structure of the gasdermin A3 membrane pore.
Ruan J, Xia S, Liu X, Lieberman J, Wu H. Ruan J, et al. Among authors: wu h. Nature. 2018 May;557(7703):62-67. doi: 10.1038/s41586-018-0058-6. Epub 2018 Apr 25. Nature. 2018. PMID: 29695864 Free PMC article.
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E. Orning P, et al. Among authors: wu h. Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. Science. 2018. PMID: 30361383 Free PMC article.
Crystal structure of the WD40 domain dimer of LRRK2.
Zhang P, Fan Y, Ru H, Wang L, Magupalli VG, Taylor SS, Alessi DR, Wu H. Zhang P, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1579-1584. doi: 10.1073/pnas.1817889116. Epub 2019 Jan 11. Proc Natl Acad Sci U S A. 2019. PMID: 30635421 Free PMC article.
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Sharif H, Wang L, Wang WL, Magupalli VG, Andreeva L, Qiao Q, Hauenstein AV, Wu Z, Núñez G, Mao Y, Wu H. Sharif H, et al. Among authors: wu h, wu z. Nature. 2019 Jun;570(7761):338-343. doi: 10.1038/s41586-019-1295-z. Epub 2019 Jun 12. Nature. 2019. PMID: 31189953 Free PMC article.
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