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Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity.
Zong X, Hao X, Xu B, Crawford JC, Wright S, Li J, Zhang Y, Bai L, He M, Jiang M, Fan Y, Connelly JP, Pruett-Miller SM, Berns H, Janke L, Li C, Feng Y. Zong X, et al. J Exp Med. 2021 Aug 2;218(8):e20202415. doi: 10.1084/jem.20202415. Epub 2021 Jun 4. J Exp Med. 2021. PMID: 34086055 Free PMC article.
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.
Karki R, Lee S, Mall R, Pandian N, Wang Y, Sharma BR, Malireddi RS, Yang D, Trifkovic S, Steele JA, Connelly JP, Vishwanath G, Sasikala M, Reddy DN, Vogel P, Pruett-Miller SM, Webby R, Jonsson CB, Kanneganti TD. Karki R, et al. Sci Immunol. 2022 Aug 26;7(74):eabo6294. doi: 10.1126/sciimmunol.abo6294. Epub 2022 Aug 26. Sci Immunol. 2022. PMID: 35587515 Free PMC article.
The protein phosphatase PP6 promotes RIPK1-dependent PANoptosis.
Bynigeri RR, Malireddi RKS, Mall R, Connelly JP, Pruett-Miller SM, Kanneganti TD. Bynigeri RR, et al. Among authors: pruett miller sm. BMC Biol. 2024 May 29;22(1):122. doi: 10.1186/s12915-024-01901-5. BMC Biol. 2024. PMID: 38807188 Free PMC article.
NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation.
Sundaram B, Pandian N, Kim HJ, Abdelaal HM, Mall R, Indari O, Sarkar R, Tweedell RE, Alonzo EQ, Klein J, Pruett-Miller SM, Vogel P, Kanneganti TD. Sundaram B, et al. Among authors: pruett miller sm. Cell. 2024 Jun 11:S0092-8674(24)00578-6. doi: 10.1016/j.cell.2024.05.034. Online ahead of print. Cell. 2024. PMID: 38878777 Free article.
139 results