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The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Pan M, Wright WC, Chapple RH, Zubair A, Sandhu M, Batchelder JE, Huddle BC, Low J, Blankenship KB, Wang Y, Gordon B, Archer P, Brady SW, Natarajan S, Posgai MJ, Schuetz J, Miller D, Kalathur R, Chen S, Connelly JP, Babu MM, Dyer MA, Pruett-Miller SM, Freeman BB 3rd, Chen T, Godley LA, Blanchard SC, Stewart E, Easton J, Geeleher P. Pan M, et al. Among authors: blanchard sc. Nat Commun. 2021 Nov 9;12(1):6468. doi: 10.1038/s41467-021-26640-x. Nat Commun. 2021. PMID: 34753908 Free PMC article.
Implications of sequence variation on the evolution of rRNA.
Parks MM, Kurylo CM, Batchelder JE, Theresa Vincent C, Blanchard SC. Parks MM, et al. Among authors: blanchard sc. Chromosome Res. 2019 Mar;27(1-2):89-93. doi: 10.1007/s10577-018-09602-w. Epub 2019 Feb 5. Chromosome Res. 2019. PMID: 30719681 Free PMC article. Review.
Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.
Prakash V, Carson BB, Feenstra JM, Dass RA, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks MM, Kurylo CM, Batchelder JE, Haller K, Hashimoto A, Rundqivst H, Condeelis JS, Allis CD, Drygin D, Nieto MA, Andäng M, Percipalle P, Bergh J, Adameyko I, Farrants AÖ, Hartman J, Lyden D, Pietras K, Blanchard SC, Vincent CT. Prakash V, et al. Among authors: blanchard sc. Nat Commun. 2019 May 8;10(1):2110. doi: 10.1038/s41467-019-10100-8. Nat Commun. 2019. PMID: 31068593 Free PMC article.
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores.
Pati AK, El Bakouri O, Jockusch S, Zhou Z, Altman RB, Fitzgerald GA, Asher WB, Terry DS, Borgia A, Holsey MD, Batchelder JE, Abeywickrama C, Huddle B, Rufa D, Javitch JA, Ottosson H, Blanchard SC. Pati AK, et al. Among authors: blanchard sc. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24305-24315. doi: 10.1073/pnas.2006517117. Epub 2020 Sep 10. Proc Natl Acad Sci U S A. 2020. PMID: 32913060 Free PMC article.
Cyanine fluorophore derivatives with enhanced photostability.
Altman RB, Terry DS, Zhou Z, Zheng Q, Geggier P, Kolster RA, Zhao Y, Javitch JA, Warren JD, Blanchard SC. Altman RB, et al. Among authors: blanchard sc. Nat Methods. 2011 Nov 13;9(1):68-71. doi: 10.1038/nmeth.1774. Nat Methods. 2011. PMID: 22081126 Free PMC article.
Transport dynamics in a glutamate transporter homologue.
Akyuz N, Altman RB, Blanchard SC, Boudker O. Akyuz N, et al. Among authors: blanchard sc. Nature. 2013 Oct 3;502(7469):114-8. doi: 10.1038/nature12265. Epub 2013 Jun 23. Nature. 2013. PMID: 23792560 Free PMC article.
137 results