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Page 1
Comparison Between Brain and Cerebellar Autoradiography Using [18F]Flortaucipir, [18F]MK6240, and [18F]PI2620 in Postmortem Human Brain Tissue.
Aliaga A, Therriault J, Quispialaya KM, Aliaga A, Hopewell R, Rahmouni N, Macedo AC, Kunach P, Soucy JP, Massarweh G, Diaz AA, Pascoal TA, Rocha A, Guiot MC, Machado LS, De Bastiani MA, de Souza DG, Souza DO, Gauthier S, Zimmer ER, Rosa-Neto P. Aliaga A, et al. Among authors: rahmouni n. J Nucl Med. 2024 Oct 30:jnumed.124.267539. doi: 10.2967/jnumed.124.267539. Online ahead of print. J Nucl Med. 2024. PMID: 39477493
Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease.
Quispialaya KM, Therriault J, Aliaga A, Tissot C, Servaes S, Rahmouni N, Karikari TK, Benedet AL, Ashton NJ, Macedo AC, Lussier FZ, Stevenson J, Wang YT, Arias JF, Hosseini A, Matsudaira T, Jean-Claude B, Gilfix BM, Zimmer ER, Soucy JP, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Quispialaya KM, et al. Among authors: rahmouni n. Eur J Neurol. 2024 Oct 24:e16255. doi: 10.1111/ene.16255. Online ahead of print. Eur J Neurol. 2024. PMID: 39447157
Cryo-EM structure of Alzheimer's disease tau filaments with PET ligand MK-6240.
Kunach P, Vaquer-Alicea J, Smith MS, Monistrol J, Hopewell R, Moquin L, Therriault J, Tissot C, Rahmouni N, Massarweh G, Soucy JP, Guiot MC, Shoichet BK, Rosa-Neto P, Diamond MI, Shahmoradian SH. Kunach P, et al. Among authors: rahmouni n. Nat Commun. 2024 Oct 1;15(1):8497. doi: 10.1038/s41467-024-52265-x. Nat Commun. 2024. PMID: 39353896 Free PMC article.
Modeling the progression of neuropsychiatric symptoms in Alzheimer's disease with PET-based Braak staging.
Macedo AC, Therriault J, Tissot C, Aumont É, Servaes S, Rahmouni N, Fernandez-Arias J, Lussier FZ, Wang YT, Ng KP, Vermeiren M, Bezgin G, Socualaya KQ, Stevenson J, Hosseini SA, Chamoun M, Ferrari-Souza JP, Ferreira PCL, Bellaver B, Leffa DT, Vitali P, Zimmer ER, Ismail Z, Pascoal TA, Gauthier S, Rosa-Neto P. Macedo AC, et al. Among authors: rahmouni n. Neurobiol Aging. 2024 Dec;144:127-137. doi: 10.1016/j.neurobiolaging.2024.09.009. Epub 2024 Sep 20. Neurobiol Aging. 2024. PMID: 39326302 Free article.
Glial reactivity is linked to synaptic dysfunction across the aging and Alzheimer's disease spectrum.
Pascoal T, Rohden F, Ferreira P, Bellaver B, Ferrari-Souza JP, Aguzzoli C, Soares C, Abbas S, Zalzale H, Povala G, Lussier F, Leffa D, Bauer-Negrini G, Rahmouni N, Tissot C, Therriault JT, Servaes S, Stevenson J, Benedet A, Ashton N, Karikari T, Tudorascu D, Zetterberg H, Blennow K, Zimmer E, Souza D, Rosa-Neto P. Pascoal T, et al. Among authors: rahmouni n. Res Sq [Preprint]. 2024 Aug 12:rs.3.rs-4782732. doi: 10.21203/rs.3.rs-4782732/v1. Res Sq. 2024. PMID: 39184102 Free PMC article. Preprint.
Hormone therapy is associated with lower Alzheimer's disease tau biomarkers in post-menopausal females -evidence from two independent cohorts.
Wang YT, Therriault J, Tissot C, Servaes S, Rahmouni N, Macedo AC, Fernandez-Arias J, Mathotaarachchi SS, Stevenson J, Lussier FZ, Benedet AL, Pascoal TA, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Rosa-Neto P. Wang YT, et al. Among authors: rahmouni n. Alzheimers Res Ther. 2024 Jul 22;16(1):162. doi: 10.1186/s13195-024-01509-5. Alzheimers Res Ther. 2024. PMID: 39034389 Free PMC article.
In-vivo neuronal dysfunction by Aβ and tau overlaps with brain-wide inflammatory mechanisms in Alzheimer's disease.
Sanchez-Rodriguez LM, Khan AF, Adewale Q, Bezgin G, Therriault J, Fernandez-Arias J, Servaes S, Rahmouni N, Tissot C, Stevenson J, Jiang H, Chai X, Carbonell F, Rosa-Neto P, Iturria-Medina Y. Sanchez-Rodriguez LM, et al. Among authors: rahmouni n. Front Aging Neurosci. 2024 Jun 19;16:1383163. doi: 10.3389/fnagi.2024.1383163. eCollection 2024. Front Aging Neurosci. 2024. PMID: 38966801 Free PMC article.
Prediction of future cognitive decline among cognitively unimpaired individuals using measures of soluble phosphorylated tau or tau tangle pathology.
Ossenkoppele R, Salvadó G, Janelidze S, Binette AP, Bali D, Karlsson L, Palmqvist S, Mattsson-Carlgren N, Stomrud E, Therriault J, Rahmouni N, Rosa-Neto P, Coomans EM, van de Giessen E, van der Flier WM, Teunissen CE, Jonaitis EM, Johnson SC; PREVENT-AD Research Group; Villeneuve S, Benzinger TLS, Schindler SE, Bateman RJ, Doecke JD, Doré V, Feizpour A, Masters CL, Rowe C, Wiste HJ, Petersen RC, Jack CR Jr, Hansson O. Ossenkoppele R, et al. Among authors: rahmouni n. medRxiv [Preprint]. 2024 Jun 13:2024.06.12.24308824. doi: 10.1101/2024.06.12.24308824. medRxiv. 2024. PMID: 38947004 Free PMC article. Preprint.
Tau follows principal axes of functional and structural brain organization in Alzheimer's disease.
Ottoy J, Kang MS, Tan JXM, Boone L, Vos de Wael R, Park BY, Bezgin G, Lussier FZ, Pascoal TA, Rahmouni N, Stevenson J, Fernandez Arias J, Therriault J, Hong SJ, Stefanovic B, McLaurin J, Soucy JP, Gauthier S, Bernhardt BC, Black SE, Rosa-Neto P, Goubran M. Ottoy J, et al. Among authors: rahmouni n. Nat Commun. 2024 Jun 12;15(1):5031. doi: 10.1038/s41467-024-49300-2. Nat Commun. 2024. PMID: 38866759 Free PMC article.
The relation of synaptic biomarkers with Aβ, tau, glial activation, and neurodegeneration in Alzheimer's disease.
Wang YT, Ashton NJ, Servaes S, Nilsson J, Woo MS, Pascoal TA, Tissot C, Rahmouni N, Therriault J, Lussier F, Chamoun M, Gauthier S, Brinkmalm A, Zetterberg H, Blennow K, Rosa-Neto P, Benedet AL. Wang YT, et al. Among authors: rahmouni n. Transl Neurodegener. 2024 May 28;13(1):27. doi: 10.1186/s40035-024-00420-1. Transl Neurodegener. 2024. PMID: 38802928 Free PMC article. No abstract available.
56 results