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An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2.
Moiani D, Link TM, Brosey CA, Katsonis P, Lichtarge O, Kim Y, Joachimiak A, Ma Z, Kim IK, Ahmed Z, Jones DE, Tsutakawa SE, Tainer JA. Moiani D, et al. Among authors: joachimiak a. Methods Enzymol. 2021;661:407-431. doi: 10.1016/bs.mie.2021.09.003. Epub 2021 Sep 27. Methods Enzymol. 2021. PMID: 34776222 Free PMC article.
Protein production for structural genomics using E. coli expression.
Makowska-Grzyska M, Kim Y, Maltseva N, Li H, Zhou M, Joachimiak G, Babnigg G, Joachimiak A. Makowska-Grzyska M, et al. Among authors: joachimiak g, joachimiak a. Methods Mol Biol. 2014;1140:89-105. doi: 10.1007/978-1-4939-0354-2_7. Methods Mol Biol. 2014. PMID: 24590711 Free PMC article.
Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Kim Y, Jedrzejczak R, Maltseva NI, Wilamowski M, Endres M, Godzik A, Michalska K, Joachimiak A. Kim Y, et al. Among authors: joachimiak a. Protein Sci. 2020 Jul;29(7):1596-1605. doi: 10.1002/pro.3873. Epub 2020 May 2. Protein Sci. 2020. PMID: 32304108 Free PMC article.
429 results