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Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex.
Patil DN, Singh S, Laboute T, Strutzenberg TS, Qiu X, Wu D, Novick SJ, Robinson CV, Griffin PR, Hunt JF, Izard T, Singh AK, Martemyanov KA. Patil DN, et al. Among authors: izard t. Science. 2022 Jan 7;375(6576):86-91. doi: 10.1126/science.abl4732. Epub 2021 Nov 18. Science. 2022. PMID: 34793198 Free PMC article.
Lipid-directed vinculin dimerization.
Chinthalapudi K, Patil DN, Rangarajan ES, Rader C, Izard T. Chinthalapudi K, et al. Among authors: izard t. Biochemistry. 2015 May 5;54(17):2758-68. doi: 10.1021/acs.biochem.5b00015. Epub 2015 Apr 24. Biochemistry. 2015. PMID: 25880222
Dual-mechanism estrogen receptor inhibitors.
Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Sanabria Guillen V, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Novick S, Pascal BD, Houtman R, Griffin PR, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min J, et al. Among authors: izard t. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2101657118. doi: 10.1073/pnas.2101657118. Proc Natl Acad Sci U S A. 2021. PMID: 34452998 Free PMC article.
81 results