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Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.
Bagal SK, Gregson C, O' Donovan DH, Pike KG, Bloecher A, Barton P, Borodovsky A, Code E, Fillery SM, Hsu JH, Kawatkar SP, Li C, Longmire D, Nai Y, Nash SC, Pike A, Robinson J, Read JA, Rawlins PB, Shen M, Tang J, Wang P, Woods H, Williamson B. Bagal SK, et al. Among authors: gregson c. J Med Chem. 2021 Dec 9;64(23):17146-17183. doi: 10.1021/acs.jmedchem.1c01161. Epub 2021 Nov 22. J Med Chem. 2021. PMID: 34807608
Free energy perturbation in the design of EED ligands as inhibitors of polycomb repressive complex 2 (PRC2) methyltransferase.
O' Donovan DH, Gregson C, Packer MJ, Greenwood R, Pike KG, Kawatkar S, Bloecher A, Robinson J, Read J, Code E, Hsu JH, Shen M, Woods H, Barton P, Fillery S, Williamson B, Rawlins PB, Bagal SK. O' Donovan DH, et al. Among authors: gregson c. Bioorg Med Chem Lett. 2021 May 1;39:127904. doi: 10.1016/j.bmcl.2021.127904. Epub 2021 Mar 6. Bioorg Med Chem Lett. 2021. PMID: 33684441
Rapid Identification of Novel Allosteric PRC2 Inhibitors.
Read JA, Tart J, Rawlins PB, Gregson C, Jones K, Gao N, Zhu X, Tomlinson R, Code E, Cheung T, Chen H, Kawatkar SP, Bloecher A, Bagal S, O'Donovan DH, Robinson J. Read JA, et al. Among authors: gregson c. ACS Chem Biol. 2019 Oct 18;14(10):2134-2140. doi: 10.1021/acschembio.9b00468. Epub 2019 Sep 23. ACS Chem Biol. 2019. PMID: 31525019
Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance.
Finlay MRV, Barton P, Bickerton S, Bista M, Colclough N, Cross DAE, Evans L, Floc'h N, Gregson C, Guérot CM, Hargreaves D, Kang X, Lenz EM, Li X, Liu Y, Lorthioir O, Martin MJ, McKerrecher D, McWhirter C, O'Neill D, Orme JP, Mosallanejad A, Rahi A, Smith PD, Talbot V, Ward RA, Wrigley G, Wylot M, Xue L, Yao T, Ye Y, Zhao X. Finlay MRV, et al. Among authors: gregson c. J Med Chem. 2021 Sep 23;64(18):13704-13718. doi: 10.1021/acs.jmedchem.1c01055. Epub 2021 Sep 7. J Med Chem. 2021. PMID: 34491761
Disparities in fragility fracture and osteoporosis care in Africa.
Ward KA, Madanhire T, Marenah K, Micklesfield LK, Gregson CL. Ward KA, et al. Among authors: gregson cl. Lancet Diabetes Endocrinol. 2024 May;12(5):294-296. doi: 10.1016/S2213-8587(24)00073-1. Epub 2024 Mar 22. Lancet Diabetes Endocrinol. 2024. PMID: 38527466 No abstract available.
Prevalence of chronic conditions and multimorbidity among healthcare workers in Zimbabwe: Results from a screening intervention.
Calderwood CJ, Marambire E, Nzvere FP, Larsson LS, Chingono RMS, Kavenga F, Redzo N, Bandason T, Rusakaniko S, Mujuru HA, Simms V, Khan P, Gregson CL, Ndhlovu CE, Ferrand RA, Fielding K, Kranzer K. Calderwood CJ, et al. Among authors: gregson cl. PLOS Glob Public Health. 2024 Jan 23;4(1):e0002630. doi: 10.1371/journal.pgph.0002630. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 38261562 Free PMC article.
Evaluation of a comprehensive health check offered to frontline health workers in Zimbabwe.
Marambire ET, Chingono RMS, Calderwood CJ, Larsson L, Sibanda S, Kavenga F, Nzvere FP, Olaru ID, Simms V, McHugh G, Bandason T, Redzo N, Gregson CL, Maunganidze AJV, Pasi C, Chiwanga M, Chonzi P, Ndhlovu CE, Mujuru H, Rusakaniko S, Ferrand RA, Kranzer K. Marambire ET, et al. Among authors: gregson cl. PLOS Glob Public Health. 2024 Jan 8;4(1):e0002328. doi: 10.1371/journal.pgph.0002328. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 38190397 Free PMC article.
146 results