Makhay M - Search Results

1

MN-166 (ibudilast) in amyotrophic lateral sclerosis in a Phase IIb/III study: COMBAT-ALS study design.

Oskarsson B, Maragakis N, Bedlack RS, Goyal N, Meyer JA, Genge A, Bodkin C, Maiser S, Staff N, Zinman L, Olney N, Turnbull J, Brooks BR, Klonowski E, Makhay M, Yasui S, Matsuda K. Oskarsson B, et al. Among authors: makhay m. Neurodegener Dis Manag. 2021 Dec;11(6):431-443. doi: 10.2217/nmt-2021-0042. Epub 2021 Nov 24. Neurodegener Dis Manag. 2021. PMID: 34816762 Free article. Clinical Trial.

2

Evaluation of bedoradrine sulfate (MN-221), a novel, highly selective beta2-adrenergic receptor agonist for the treatment of asthma via intravenous infusion.

Matsuda K, Makhay M, Johnson K, Iwaki Y. Matsuda K, et al. Among authors: makhay m. J Asthma. 2012 Dec;49(10):1071-8. doi: 10.3109/02770903.2012.729631. Epub 2012 Oct 25. J Asthma. 2012. PMID: 23094708 Clinical Trial.

3

Efficacy of a new intravenous β2-adrenergic agonist (bedoradrine, MN-221) for patients with an acute exacerbation of asthma.

House SL, Matsuda K, O'Brien G, Makhay M, Iwaki Y, Ferguson I, Lovato LM, Lewis LM. House SL, et al. Among authors: makhay m. Respir Med. 2015 Oct;109(10):1268-73. doi: 10.1016/j.rmed.2015.08.003. Epub 2015 Aug 14. Respir Med. 2015. PMID: 26324315 Free article. Clinical Trial.

4

Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats.

Makhay MM, Houslay MD, O'Donnell JM. Makhay MM, et al. Psychopharmacology (Berl). 2001 Nov;158(3):297-304. doi: 10.1007/s002130100878. Psychopharmacology (Berl). 2001. PMID: 11713620

5

Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist.

Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, Andersson CM, Tolf BR, Brann MR, Hacksell U, Davis RE. Vanover KE, et al. Among authors: makhay m. J Pharmacol Exp Ther. 2004 Sep;310(3):943-51. doi: 10.1124/jpet.104.066688. Epub 2004 Apr 21. J Pharmacol Exp Ther. 2004. PMID: 15102927

6

Discriminative stimulus effects of centrally administered isoproterenol in rats: mediation by beta-1 adrenergic receptors.

Crissman AM, Makhay MM, O'Donnell JM. Crissman AM, et al. Among authors: makhay mm. Psychopharmacology (Berl). 2001 Feb;154(1):70-5. doi: 10.1007/s002130000618. Psychopharmacology (Berl). 2001. PMID: 11292008

7

Effects of antidepressants in rats trained to discriminate the beta-2 adrenergic agonist clenbuterol.

Makhay MM, O'Donnell JM. Makhay MM, et al. Pharmacol Biochem Behav. 1999 Jun;63(2):319-24. doi: 10.1016/s0091-3057(98)00266-4. Pharmacol Biochem Behav. 1999. PMID: 10371662

8

Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain.

Farooqui SM, Zhang K, Makhay M, Jackson K, Farooqui SQ, Cherry JA, O'Donnell JM. Farooqui SM, et al. Among authors: makhay m. Brain Res. 2000 Jun 9;867(1-2):52-61. doi: 10.1016/s0006-8993(00)02224-1. Brain Res. 2000. PMID: 10837797

9

Behavioral contingencies modulate tolerance to discriminative stimulus effects of morphine.

Young AM, McMullen WJ, Makhay MM, Goushaw PJ. Young AM, et al. Among authors: makhay mm. Psychopharmacology (Berl). 1996 Jun;125(3):220-30. doi: 10.1007/BF02247332. Psychopharmacology (Berl). 1996. PMID: 8815957

10

Establishing morphine and U-50,488H as discriminative stimuli in a three-choice assay with pigeons.

Makhay MM, Young AM, Poling A. Makhay MM, et al. Exp Clin Psychopharmacol. 1998 Feb;6(1):3-9. doi: 10.1037//1064-1297.6.1.3. Exp Clin Psychopharmacol. 1998. PMID: 9526141

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