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Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation.
Al-Ansary GH, Eldehna WM, Ghabbour HA, Al-Rashood STA, Al-Rashood KA, Eladwy RA, Al-Dhfyan A, Kabil MM, Abdel-Aziz HA. Al-Ansary GH, et al. Among authors: eldehna wm. J Enzyme Inhib Med Chem. 2017 Dec;32(1):986-991. doi: 10.1080/14756366.2017.1347166. J Enzyme Inhib Med Chem. 2017. PMID: 28726519 Free PMC article.
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents.
Eldehna WM, Abo-Ashour MF, Nocentini A, El-Haggar RS, Bua S, Bonardi A, Al-Rashood ST, Hassan GS, Gratteri P, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Eur J Med Chem. 2019 Jan 15;162:147-160. doi: 10.1016/j.ejmech.2018.10.068. Epub 2018 Nov 2. Eur J Med Chem. 2019. PMID: 30445264
197 results