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A scalable and robust cationic lipid/polymer hybrid nanoparticle platform for mRNA delivery.
Int J Pharm. 2022 Jan 5;611:121314. doi: 10.1016/j.ijpharm.2021.121314. Epub 2021 Nov 25.
Int J Pharm. 2022.
PMID: 34838950
pH-Dependent Phase Behavior and Stability of Cationic Lipid-mRNA Nanoparticles.
Larson NR, Hu G, Wei Y, Tuesca AD, Forrest ML, Middaugh CR.
Larson NR, et al. Among authors: tuesca ad.
J Pharm Sci. 2022 Mar;111(3):690-698. doi: 10.1016/j.xphs.2021.11.004. Epub 2021 Nov 12.
J Pharm Sci. 2022.
PMID: 34774918
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High-throughput and high-content bioassay enables tuning of polyester nanoparticles for cellular uptake, endosomal escape, and systemic in vivo delivery of mRNA.
Rui Y, Wilson DR, Tzeng SY, Yamagata HM, Sudhakar D, Conge M, Berlinicke CA, Zack DJ, Tuesca A, Green JJ.
Rui Y, et al.
Sci Adv. 2022 Jan 7;8(1):eabk2855. doi: 10.1126/sciadv.abk2855. Epub 2022 Jan 5.
Sci Adv. 2022.
PMID: 34985952
Free PMC article.
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Complexation hydrogels for oral insulin delivery: effects of polymer dosing on in vivo efficacy.
Tuesca A, Nakamura K, Morishita M, Joseph J, Peppas N, Lowman A.
Tuesca A, et al.
J Pharm Sci. 2008 Jul;97(7):2607-18. doi: 10.1002/jps.21184.
J Pharm Sci. 2008.
PMID: 17876768
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Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer.
Chen F, Ma K, Madajewski B, Zhuang L, Zhang L, Rickert K, Marelli M, Yoo B, Turker MZ, Overholtzer M, Quinn TP, Gonen M, Zanzonico P, Tuesca A, Bowen MA, Norton L, Subramony JA, Wiesner U, Bradbury MS.
Chen F, et al.
Nat Commun. 2018 Oct 8;9(1):4141. doi: 10.1038/s41467-018-06271-5.
Nat Commun. 2018.
PMID: 30297810
Free PMC article.
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Composite iron oxide-Prussian blue nanoparticles for magnetically guided T1-weighted magnetic resonance imaging and photothermal therapy of tumors.
Kale SS, Burga RA, Sweeney EE, Zun Z, Sze RW, Tuesca A, Subramony JA, Fernandes R.
Kale SS, et al.
Int J Nanomedicine. 2017 Sep 5;12:6413-6424. doi: 10.2147/IJN.S144515. eCollection 2017.
Int J Nanomedicine. 2017.
PMID: 28919744
Free PMC article.
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Synthesis, characterization and in vivo efficacy of PEGylated insulin for oral delivery with complexation hydrogels.
Tuesca AD, Reiff C, Joseph JI, Lowman AM.
Tuesca AD, et al.
Pharm Res. 2009 Mar;26(3):727-39. doi: 10.1007/s11095-008-9816-8. Epub 2009 Jan 15.
Pharm Res. 2009.
PMID: 19145407
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Complexation hydrogels for oral protein delivery: an in vitro assessment of the insulin transport-enhancing effects following dissolution in simulated digestive fluids.
Perakslis E, Tuesca A, Lowman A.
Perakslis E, et al.
J Biomater Sci Polym Ed. 2007;18(12):1475-90.
J Biomater Sci Polym Ed. 2007.
PMID: 17988515
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