Hesselink DA - Search Results

1

A randomized crossover study comparing different tacrolimus formulations to reduce intrapatient variability in tacrolimus exposure in kidney transplant recipients.

Bunthof KLW, Al-Hassany L, Nakshbandi G, Hesselink DA, van Schaik RHN, Ten Dam MAGJ, Baas MC, Hilbrands LB, van Gelder T. Bunthof KLW, et al. Among authors: hesselink da. Clin Transl Sci. 2022 Apr;15(4):930-941. doi: 10.1111/cts.13206. Epub 2021 Dec 15. Clin Transl Sci. 2022. PMID: 34905302 Free PMC article. Clinical Trial.

2

Tacrolimus dose requirement in renal transplant recipients is significantly higher when used in combination with corticosteroids.

Hesselink DA, Ngyuen H, Wabbijn M, Gregoor PJ, Steyerberg EW, van Riemsdijk IC, Weimar W, van Gelder T. Hesselink DA, et al. Br J Clin Pharmacol. 2003 Sep;56(3):327-30. doi: 10.1046/j.0306-5251.2003.01882.x. Br J Clin Pharmacol. 2003. PMID: 12919182 Free PMC article. Clinical Trial.

3

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus.

Hesselink DA, van Schaik RH, van der Heiden IP, van der Werf M, Gregoor PJ, Lindemans J, Weimar W, van Gelder T. Hesselink DA, et al. Clin Pharmacol Ther. 2003 Sep;74(3):245-54. doi: 10.1016/S0009-9236(03)00168-1. Clin Pharmacol Ther. 2003. PMID: 12966368

4

Pharmacogenetics in immunosuppressive therapy: the best thing since TDM?

van Gelder T, Hesselink DA, van Hest RM, Mathôt RA, van Schaik R. van Gelder T, et al. Among authors: hesselink da. Ther Drug Monit. 2004 Aug;26(4):343-6. doi: 10.1097/00007691-200408000-00001. Ther Drug Monit. 2004. PMID: 15257061 Review. No abstract available.

5

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

Hesselink DA, van Gelder T, van Schaik RH, Balk AH, van der Heiden IP, van Dam T, van der Werf M, Weimar W, Mathot RA. Hesselink DA, et al. Clin Pharmacol Ther. 2004 Dec;76(6):545-56. doi: 10.1016/j.clpt.2004.08.022. Clin Pharmacol Ther. 2004. PMID: 15592326

6

Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.

Hesselink DA, van Hest RM, Mathot RA, Bonthuis F, Weimar W, de Bruin RW, van Gelder T. Hesselink DA, et al. Am J Transplant. 2005 May;5(5):987-94. doi: 10.1046/j.1600-6143.2005.00779.x. Am J Transplant. 2005. PMID: 15816878 Free article.

7

The pharmacogenetics of calcineurin inhibitors: one step closer toward individualized immunosuppression?

Hesselink DA, van Gelder T, van Schaik RH. Hesselink DA, et al. Pharmacogenomics. 2005 Jun;6(4):323-37. doi: 10.1517/14622416.6.4.323. Pharmacogenomics. 2005. PMID: 16004552 Review.

8

Clinical outcome after cyclosporine dose reduction based on C2 levels in long-term liver transplant patients.

Tha-In T, Hesselink DA, Tilanus HW, Elshove L, Wilschut AL, Hansen BE, van Gelder T, Metselaar HJ. Tha-In T, et al. Among authors: hesselink da. Clin Transplant. 2005 Aug;19(4):537-42. doi: 10.1111/j.1399-0012.2005.00385.x. Clin Transplant. 2005. PMID: 16008602

9

Genetic and nongenetic determinants of between-patient variability in the pharmacokinetics of mycophenolic acid.

Hesselink DA, van Gelder T. Hesselink DA, et al. Clin Pharmacol Ther. 2005 Oct;78(4):317-21. doi: 10.1016/j.clpt.2005.06.008. Clin Pharmacol Ther. 2005. PMID: 16198650 Review. No abstract available.

10

Individualization of mycophenolate mofetil dose in renal transplant recipients.

van Hest RM, Hesselink DA, Vulto AG, Mathot RA, van Gelder T. van Hest RM, et al. Among authors: hesselink da. Expert Opin Pharmacother. 2006 Mar;7(4):361-76. doi: 10.1517/14656566.7.4.361. Expert Opin Pharmacother. 2006. PMID: 16503809 Review.

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