Murphy JE - Search Results

1

AAV-mediated expression of galactose-1-phosphate uridyltransferase corrects defects of galactose metabolism in classic galactosemia patient fibroblasts.

Brophy ML, Stansfield JC, Ahn Y, Cheng SH, Murphy JE, Bell RD. Brophy ML, et al. Among authors: murphy je. J Inherit Metab Dis. 2022 May;45(3):481-492. doi: 10.1002/jimd.12468. Epub 2022 Jan 23. J Inherit Metab Dis. 2022. PMID: 34918784

2

Assessment of galactose-1-phosphate uridyltransferase activity in cells and tissues.

Brophy ML, Murphy JE, Bell RD. Brophy ML, et al. Among authors: murphy je. J Biol Methods. 2021 Jun 30;8(2):e149. doi: 10.14440/jbm.2021.355. eCollection 2021. J Biol Methods. 2021. PMID: 34258307 Free PMC article.

3

Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model.

Pittman DD, Rakhe S, Bowley SR, Jasuja R, Barakat A, Murphy JE. Pittman DD, et al. Among authors: murphy je. Res Pract Thromb Haemost. 2022 Mar 16;6(2):e12679. doi: 10.1002/rth2.12679. eCollection 2022 Feb. Res Pract Thromb Haemost. 2022. PMID: 35316941 Free PMC article.

4

PF-07059013: A non-covalent hemoglobin modulator favorably impacts disease state in a mouse model of sickle cell disease.

Knee KM, Jasuja R, Barakat A, Rao D, Wenzel Z, Jasti J, Novak J, Beaumont K, Piotrowski DW, Jeffrey P, Bulawa C, Murphy JE, Janz JM. Knee KM, et al. Among authors: murphy je. Am J Hematol. 2021 Aug 1;96(8):E272-E275. doi: 10.1002/ajh.26204. Epub 2021 May 13. Am J Hematol. 2021. PMID: 33891711 Free PMC article. No abstract available.

5

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia.

Arezes J, Foy N, McHugh K, Quinkert D, Benard S, Sawant A, Frost JN, Armitage AE, Pasricha SR, Lim PJ, Tam MS, Lavallie E, Pittman DD, Cunningham O, Lambert M, Murphy JE, Draper SJ, Jasuja R, Drakesmith H. Arezes J, et al. Among authors: murphy je. Blood. 2020 Feb 20;135(8):547-557. doi: 10.1182/blood.2019003140. Blood. 2020. PMID: 31899794 Free PMC article.

6

Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas.

Patel-Hett S, Martin EJ, Mohammed BM, Rakhe S, Sun P, Barrett JC, Nolte ME, Kuhn J, Pittman DD, Murphy JE, Brophy DF. Patel-Hett S, et al. Among authors: murphy je. Haemophilia. 2019 Sep;25(5):797-806. doi: 10.1111/hae.13820. Epub 2019 Jul 23. Haemophilia. 2019. PMID: 31336410

7

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.

Parng C, Singh P, Pittman DD, Wright K, Leary B, Patel-Hett S, Rakhe S, Stejskal J, Peraza M, Dufield D, Murphy JE, Webster R. Parng C, et al. Among authors: murphy je. J Pharm Sci. 2018 Jul;107(7):1995-2004. doi: 10.1016/j.xphs.2018.03.010. Epub 2018 Mar 20. J Pharm Sci. 2018. PMID: 29571739

8

A first-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-06741086, an anti-tissue factor pathway inhibitor mAb, in healthy volunteers.

Cardinal M, Kantaridis C, Zhu T, Sun P, Pittman DD, Murphy JE, Arkin S. Cardinal M, et al. Among authors: murphy je. J Thromb Haemost. 2018 Sep;16(9):1722-1731. doi: 10.1111/jth.14207. Epub 2018 Jul 20. J Thromb Haemost. 2018. PMID: 29908043 Free article. Clinical Trial.

9

Factor IX assay discrepancies in the setting of liver gene therapy using a hyperfunctional variant factor IX-Padua.

Robinson MM, George LA, Carr ME, Samelson-Jones BJ, Arruda VR, Murphy JE, Rybin D, Rupon J, High KA, Tiefenbacher S. Robinson MM, et al. Among authors: murphy je. J Thromb Haemost. 2021 May;19(5):1212-1218. doi: 10.1111/jth.15281. Epub 2021 Mar 28. J Thromb Haemost. 2021. PMID: 33636038 Free PMC article.

10

Implementation, Reach, and Effectiveness of the Direct Observation of Residents in Clinic Program.

Murphy JE, Khawaja H, Messina D, Monteiro JFG, Jeremiah J, McGarry K. Murphy JE, et al. Educ Health (Abingdon). 2023 Sep 1;36(3):104-110. doi: 10.4103/efh.efh_90_23. Epub 2023 Dec 22. Educ Health (Abingdon). 2023. PMID: 38133125 Free article.

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