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Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
Gerckens M, Schorpp K, Pelizza F, Wögrath M, Reichau K, Ma H, Dworsky AM, Sengupta A, Stoleriu MG, Heinzelmann K, Merl-Pham J, Irmler M, Alsafadi HN, Trenkenschuh E, Sarnova L, Jirouskova M, Frieß W, Hauck SM, Beckers J, Kneidinger N, Behr J, Hilgendorff A, Hadian K, Lindner M, Königshoff M, Eickelberg O, Gregor M, Plettenburg O, Yildirim AÖ, Burgstaller G. Gerckens M, et al. Among authors: hilgendorff a. Sci Adv. 2021 Dec 24;7(52):eabb3673. doi: 10.1126/sciadv.abb3673. Epub 2021 Dec 22. Sci Adv. 2021. PMID: 34936468 Free PMC article.
Granulocyte Colony-Stimulating Factor is a Determinant of Severe Bronchopulmonary Dysplasia and Coincident Retinopathy.
Wickramasinghe LC, Tsantikos E, Kindt A, Raftery AL, Gottschalk TA, Borger JG, Malhotra A, Anderson GP, van Wijngaarden P, Hilgendorff A, Hibbs ML. Wickramasinghe LC, et al. Among authors: hilgendorff a. Am J Pathol. 2023 Dec;193(12):2001-2016. doi: 10.1016/j.ajpath.2023.07.006. Epub 2023 Sep 9. Am J Pathol. 2023. PMID: 37673326 Free article.
Early Identification of Bronchopulmonary Dysplasia Using Novel Biomarkers by Proteomic Screening.
Förster K, Sass S, Ehrhardt H, Mous DS, Rottier RJ, Oak P, Schulze A, Flemmer AW, Gronbach J, Hübener C, Desai T, Eickelberg O, Theis FJ, Hilgendorff A. Förster K, et al. Among authors: hilgendorff a. Am J Respir Crit Care Med. 2018 Apr 15;197(8):1076-1080. doi: 10.1164/rccm.201706-1218LE. Am J Respir Crit Care Med. 2018. PMID: 29053024 No abstract available.
Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
Heinzelmann K, Lehmann M, Gerckens M, Noskovičová N, Frankenberger M, Lindner M, Hatz R, Behr J, Hilgendorff A, Königshoff M, Eickelberg O. Heinzelmann K, et al. Among authors: hilgendorff a. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L682-L696. doi: 10.1152/ajplung.00439.2017. Epub 2018 Jun 28. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29952218 Free article.
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.
Lehmann M, Buhl L, Alsafadi HN, Klee S, Hermann S, Mutze K, Ota C, Lindner M, Behr J, Hilgendorff A, Wagner DE, Königshoff M. Lehmann M, et al. Among authors: hilgendorff a. Respir Res. 2018 Sep 15;19(1):175. doi: 10.1186/s12931-018-0876-y. Respir Res. 2018. PMID: 30219058 Free PMC article.
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis.
Strunz M, Simon LM, Ansari M, Kathiriya JJ, Angelidis I, Mayr CH, Tsidiridis G, Lange M, Mattner LF, Yee M, Ogar P, Sengupta A, Kukhtevich I, Schneider R, Zhao Z, Voss C, Stoeger T, Neumann JHL, Hilgendorff A, Behr J, O'Reilly M, Lehmann M, Burgstaller G, Königshoff M, Chapman HA, Theis FJ, Schiller HB. Strunz M, et al. Among authors: hilgendorff a. Nat Commun. 2020 Jul 16;11(1):3559. doi: 10.1038/s41467-020-17358-3. Nat Commun. 2020. PMID: 32678092 Free PMC article.
100 results