Okamoto H - Search Results

1

Evaluating the Safety, Tolerability, and Disposition of Trazpiroben, a D₂ /D₃ Receptor Antagonist: Phase I Single- and Multiple-Ascending Dose Studies in Healthy Japanese Participants.

Yamaguchi T, Kudou K, Okamoto H, Chen C, Whiting R, Sekino H. Yamaguchi T, et al. Among authors: okamoto h. Clin Pharmacol Drug Dev. 2022 Jun;11(6):695-706. doi: 10.1002/cpdd.1057. Epub 2021 Dec 29. Clin Pharmacol Drug Dev. 2022. PMID: 34967147 Free PMC article. Clinical Trial.

2

Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects.

Jenkins H, Sakurai Y, Nishimura A, Okamoto H, Hibberd M, Jenkins R, Yoneyama T, Ashida K, Ogama Y, Warrington S. Jenkins H, et al. Among authors: okamoto h. Aliment Pharmacol Ther. 2015 Apr;41(7):636-48. doi: 10.1111/apt.13121. Epub 2015 Feb 23. Aliment Pharmacol Ther. 2015. PMID: 25707624 Free PMC article. Clinical Trial.

3

Pharmacokinetics and Safety of Triple Therapy with Vonoprazan, Amoxicillin, and Clarithromycin or Metronidazole: A Phase 1, Open-Label, Randomized, Crossover Study.

Sakurai Y, Shiino M, Okamoto H, Nishimura A, Nakamura K, Hasegawa S. Sakurai Y, et al. Among authors: okamoto h. Adv Ther. 2016 Sep;33(9):1519-35. doi: 10.1007/s12325-016-0374-x. Epub 2016 Jul 18. Adv Ther. 2016. PMID: 27432383 Clinical Trial.

4

Pharmacokinetics of a Single Dose of Azilsartan in Pediatric Patients: A Phase 3, Open-Label, Multicenter Study.

Enya K, Saji BT, Kato T, Okamoto H, Koumura E. Enya K, et al. Among authors: okamoto h. Adv Ther. 2018 Aug;35(8):1181-1190. doi: 10.1007/s12325-018-0754-5. Epub 2018 Jul 19. Adv Ther. 2018. PMID: 30027478 Free PMC article. Clinical Trial.

5

A Phase 1, Multiple-Dose Study of Vedolizumab in Japanese Patients With Ulcerative Colitis.

Kobayashi K, Suzuki Y, Watanabe K, Oda K, Mukae M, Yamada A, Yamagami H, Nishimura A, Okamoto H. Kobayashi K, et al. Among authors: okamoto h. J Clin Pharmacol. 2019 Feb;59(2):271-279. doi: 10.1002/jcph.1307. Epub 2018 Sep 7. J Clin Pharmacol. 2019. PMID: 30192378 Free PMC article. Clinical Trial.

6

Pharmacokinetics and Safety of Vedolizumab Following Administration of a Single Intravenous Dose in Healthy Chinese Subjects.

Xie R, Zhao N, Jia B, Zhao X, Cui Y, Okamoto H, Yang L, Prokopienko A. Xie R, et al. Among authors: okamoto h. Eur J Drug Metab Pharmacokinet. 2023 Jan;48(1):35-40. doi: 10.1007/s13318-022-00804-6. Epub 2022 Nov 18. Eur J Drug Metab Pharmacokinet. 2023. PMID: 36400983 Free PMC article.

7

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising TAK-438 (Vonoprazan) Doses in Healthy Male Japanese/non-Japanese Subjects.

Sakurai Y, Nishimura A, Kennedy G, Hibberd M, Jenkins R, Okamoto H, Yoneyama T, Jenkins H, Ashida K, Irie S, Täubel J. Sakurai Y, et al. Among authors: okamoto h. Clin Transl Gastroenterol. 2015 Jun 25;6(6):e94. doi: 10.1038/ctg.2015.18. Clin Transl Gastroenterol. 2015. PMID: 26111126 Free PMC article.

8

Pharmacokinetic Drug-Drug Interactions Between Vonoprazan and Low-Dose Aspirin or Nonsteroidal Anti-inflammatory Drugs: A Phase 2, Open-Label, Study in Healthy Japanese Men.

Sakurai Y, Shiino M, Horii S, Okamoto H, Nakamura K, Nishimura A, Sakata Y. Sakurai Y, et al. Among authors: okamoto h. Clin Drug Investig. 2017 Jan;37(1):39-49. doi: 10.1007/s40261-016-0455-2. Clin Drug Investig. 2017. PMID: 27581248 Free PMC article. Clinical Trial.

9

[A phase II pharmacological study of leuprolide acetate 6-month depot, TAP-144-SR (6M), in treatment-Nazve patients with prostatic cancer who received a single subcutaneous or intramuscular injection].

Komura E, Fujimoto T, Takabayashi N, Okamoto H, Akaza H. Komura E, et al. Among authors: okamoto h. Gan To Kagaku Ryoho. 2014 May;41(5):587-93. Gan To Kagaku Ryoho. 2014. PMID: 24917003 Clinical Trial. Japanese.

10

Acid-inhibitory effects of vonoprazan 20 mg compared with esomeprazole 20 mg or rabeprazole 10 mg in healthy adult male subjects--a randomised open-label cross-over study.

Sakurai Y, Mori Y, Okamoto H, Nishimura A, Komura E, Araki T, Shiramoto M. Sakurai Y, et al. Among authors: okamoto h. Aliment Pharmacol Ther. 2015 Sep;42(6):719-30. doi: 10.1111/apt.13325. Epub 2015 Jul 21. Aliment Pharmacol Ther. 2015. PMID: 26193978 Free article. Clinical Trial.

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