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Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair.
Nat Struct Mol Biol. 2022 Jan;29(1):59-66. doi: 10.1038/s41594-021-00707-1. Epub 2022 Jan 10.
Nat Struct Mol Biol. 2022.
PMID: 35013597
MutL binds to 3' resected DNA ends and blocks DNA polymerase access.
Borsellini A, Lebbink JHG, Lamers MH.
Borsellini A, et al.
Nucleic Acids Res. 2022 Jun 24;50(11):6224-6234. doi: 10.1093/nar/gkac432.
Nucleic Acids Res. 2022.
PMID: 35670670
Free PMC article.
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DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis.
Chengalroyen MD, Mason MK, Borsellini A, Tassoni R, Abrahams GL, Lynch S, Ahn YM, Ambler J, Young K, Crowley BM, Olsen DB, Warner DF, Barry Iii CE, Boshoff HIM, Lamers MH, Mizrahi V.
Chengalroyen MD, et al. Among authors: borsellini a.
ACS Infect Dis. 2022 Mar 11;8(3):612-625. doi: 10.1021/acsinfecdis.1c00643. Epub 2022 Feb 10.
ACS Infect Dis. 2022.
PMID: 35143160
Free PMC article.
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A four-point molecular handover during Okazaki maturation.
Botto MM, Borsellini A, Lamers MH.
Botto MM, et al. Among authors: borsellini a.
Nat Struct Mol Biol. 2023 Oct;30(10):1505-1515. doi: 10.1038/s41594-023-01071-y. Epub 2023 Aug 24.
Nat Struct Mol Biol. 2023.
PMID: 37620586
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