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YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer.
Jiang D, Qiu T, Peng J, Li S, Tala, Ren W, Yang C, Wen Y, Chen CH, Sun J, Wu Y, Liu R, Zhou J, Wu K, Liu W, Mao X, Zhou Z, Chen C. Jiang D, et al. Among authors: chen ch, chen c. Cell Death Differ. 2022 Jun;29(6):1283-1295. doi: 10.1038/s41418-021-00920-x. Epub 2022 Jan 13. Cell Death Differ. 2022. PMID: 35022570 Free PMC article.
Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer.
Wang X, Qiu T, Wu Y, Yang C, Li Y, Du G, He Y, Liu W, Liu R, Chen CH, Shi Y, Pan J, Zhou J, Jiang D, Chen C. Wang X, et al. Among authors: chen ch, chen c. Cell Death Differ. 2021 Oct;28(10):2931-2945. doi: 10.1038/s41418-021-00793-0. Epub 2021 May 10. Cell Death Differ. 2021. PMID: 33972717 Free PMC article.
Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution.
He JX, Wang M, Huan XJ, Chen CH, Song SS, Wang YQ, Liao XM, Tan C, He Q, Tong LJ, Wang YT, Li XH, Su Y, Shen YY, Sun YM, Yang XY, Chen Y, Gao ZW, Chen XY, Xiong B, Lu XL, Ding J, Yang CH, Miao ZH. He JX, et al. Among authors: chen xy, chen ch, chen y. Oncotarget. 2017 Jan 17;8(3):4156-4168. doi: 10.18632/oncotarget.13749. Oncotarget. 2017. PMID: 27926532 Free PMC article.
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