Hansen DF - Search Results

1

Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2.

Soloviev Z, Bullock JMA, James JMB, Sauerwein AC, Nettleship JE, Owens RJ, Hansen DF, Topf M, Thalassinos K. Soloviev Z, et al. Among authors: hansen df. Biochim Biophys Acta Proteins Proteom. 2022 Mar 1;1870(3):140759. doi: 10.1016/j.bbapap.2022.140759. Epub 2022 Jan 18. Biochim Biophys Acta Proteins Proteom. 2022. PMID: 35051665 Free PMC article.

2

Loop interactions and dynamics tune the enzymatic activity of the human histone deacetylase 8.

Kunze MB, Wright DW, Werbeck ND, Kirkpatrick J, Coveney PV, Hansen DF. Kunze MB, et al. Among authors: hansen df. J Am Chem Soc. 2013 Nov 27;135(47):17862-8. doi: 10.1021/ja408184x. Epub 2013 Nov 15. J Am Chem Soc. 2013. PMID: 24171457 Free PMC article.

3

Solution structure of the major factor VIII binding region on von Willebrand factor.

Shiltagh N, Kirkpatrick J, Cabrita LD, McKinnon TA, Thalassinos K, Tuddenham EG, Hansen DF. Shiltagh N, et al. Among authors: hansen df. Blood. 2014 Jun 26;123(26):4143-51. doi: 10.1182/blood-2013-07-517086. Epub 2014 Apr 3. Blood. 2014. PMID: 24700780 Free PMC article.

4

Probing arginine side-chains and their dynamics with carbon-detected NMR spectroscopy: application to the 42 kDa human histone deacetylase 8 at high pH.

Werbeck ND, Kirkpatrick J, Hansen DF. Werbeck ND, et al. Among authors: hansen df. Angew Chem Int Ed Engl. 2013 Mar 11;52(11):3145-7. doi: 10.1002/anie.201209385. Epub 2013 Feb 10. Angew Chem Int Ed Engl. 2013. PMID: 23401322 Free PMC article. No abstract available.

5

Potent non-hydroxamate inhibitors of histone deacetylase-8: Role and scope of an isoindolin-2-yl linker with an α-amino amide as the zinc-binding unit.

Greenwood SOR, Chan AWE, Hansen DF, Marson CM. Greenwood SOR, et al. Among authors: hansen df. Bioorg Med Chem Lett. 2020 Mar 1;30(5):126926. doi: 10.1016/j.bmcl.2019.126926. Epub 2020 Jan 9. Bioorg Med Chem Lett. 2020. PMID: 31952961

6

A distal regulatory region of a class I human histone deacetylase.

Werbeck ND, Shukla VK, Kunze MBA, Yalinca H, Pritchard RB, Siemons L, Mondal S, Greenwood SOR, Kirkpatrick J, Marson CM, Hansen DF. Werbeck ND, et al. Among authors: hansen df. Nat Commun. 2020 Jul 31;11(1):3841. doi: 10.1038/s41467-020-17610-w. Nat Commun. 2020. PMID: 32737323 Free PMC article.

7

Aromatic side-chain flips orchestrate the conformational sampling of functional loops in human histone deacetylase 8.

Shukla VK, Siemons L, Gervasio FL, Hansen DF. Shukla VK, et al. Among authors: hansen df. Chem Sci. 2021 May 27;12(27):9318-9327. doi: 10.1039/d1sc01929e. eCollection 2021 Jul 14. Chem Sci. 2021. PMID: 34349901 Free PMC article.

8

Intrinsic structural dynamics dictate enzymatic activity and inhibition.

Shukla VK, Siemons L, Hansen DF. Shukla VK, et al. Among authors: hansen df. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2310910120. doi: 10.1073/pnas.2310910120. Epub 2023 Oct 2. Proc Natl Acad Sci U S A. 2023. PMID: 37782780 Free PMC article.

9

Measurement of bond vector orientations in invisible excited states of proteins.

Vallurupalli P, Hansen DF, Stollar E, Meirovitch E, Kay LE. Vallurupalli P, et al. Among authors: hansen df. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18473-7. doi: 10.1073/pnas.0708296104. Epub 2007 Nov 15. Proc Natl Acad Sci U S A. 2007. PMID: 18006656 Free PMC article.

10

Using ¹⁵N-ammonium to characterise and map potassium binding sites in proteins by NMR spectroscopy.

Werbeck ND, Kirkpatrick J, Reinstein J, Hansen DF. Werbeck ND, et al. Among authors: hansen df. Chembiochem. 2014 Mar 3;15(4):543-8. doi: 10.1002/cbic.201300700. Epub 2014 Feb 12. Chembiochem. 2014. PMID: 24520048 Free PMC article.

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