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Understanding potential participation barriers to improve trial design and outcomes: clinical trial simulation in palmoplantar pustulosis as a case study.
Boisvert-Huneault C, Trigos Herraez D, Pinter A, Kobayashi S, Bell S, Kallsen K, Gloede T, Yagi N, Brunette S, Datsenko Y, Baehner F, Clerisme-Beaty E, Van de Kerkhof P. Boisvert-Huneault C, et al. Among authors: brunette s. BMJ Open. 2023 Apr 24;13(4):e064159. doi: 10.1136/bmjopen-2022-064159. BMJ Open. 2023. PMID: 37094891 Free PMC article.
A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay.
Kashem MA, Kennedy CA, Fogarty KE, Dimock JR, Zhang Y, Sanville-Ross ML, Skow DJ, Brunette SR, Swantek JL, Hummel HS, Swindle J, Nelson RM. Kashem MA, et al. Among authors: brunette sr. Assay Drug Dev Technol. 2016 Jan-Feb;14(1):39-49. doi: 10.1089/adt.2015.671. Epub 2015 Oct 1. Assay Drug Dev Technol. 2016. PMID: 26426296
Discovery of a Series of Pyrazinone RORγ Antagonists and Identification of the Clinical Candidate BI 730357.
Harcken C, Csengery J, Turner M, Wu L, Liang S, Sibley R, Brunette S, Labadia M, Hoyt K, Wayne A, Wieckowski T, Davis G, Panzenbeck M, Souza D, Kugler S, Terenzio D, Collin D, Smith D, Fryer RM, Tseng YC, Hehn JP, Fletcher K, Hughes RO. Harcken C, et al. Among authors: brunette s. ACS Med Chem Lett. 2021 Jan 5;12(1):143-154. doi: 10.1021/acsmedchemlett.0c00575. eCollection 2021 Jan 14. ACS Med Chem Lett. 2021. PMID: 33488976 Free PMC article.
Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart.
Abdul-Ghani M, Suen C, Jiang B, Deng Y, Weldrick JJ, Putinski C, Brunette S, Fernando P, Lee TT, Flynn P, Leenen FHH, Burgon PG, Stewart DJ, Megeney LA. Abdul-Ghani M, et al. Among authors: brunette s. Cell Res. 2017 Oct;27(10):1195-1215. doi: 10.1038/cr.2017.87. Epub 2017 Aug 8. Cell Res. 2017. PMID: 28785017 Free PMC article.
27 results