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Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment.
Adeleye Y, Andersen M, Clewell R, Davies M, Dent M, Edwards S, Fowler P, Malcomber S, Nicol B, Scott A, Scott S, Sun B, Westmoreland C, White A, Zhang Q, Carmichael PL. Adeleye Y, et al. Among authors: carmichael pl. Toxicology. 2015 Jun 5;332:102-11. doi: 10.1016/j.tox.2014.02.007. Epub 2014 Feb 25. Toxicology. 2015. PMID: 24582757 Free article.
Vision of a near future: Bridging the human health-environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment.
Rivetti C, Allen TEH, Brown JB, Butler E, Carmichael PL, Colbourne JK, Dent M, Falciani F, Gunnarsson L, Gutsell S, Harrill JA, Hodges G, Jennings P, Judson R, Kienzler A, Margiotta-Casaluci L, Muller I, Owen SF, Rendal C, Russell PJ, Scott S, Sewell F, Shah I, Sorrel I, Viant MR, Westmoreland C, White A, Campos B. Rivetti C, et al. Among authors: carmichael pl. Toxicol In Vitro. 2020 Feb;62:104692. doi: 10.1016/j.tiv.2019.104692. Epub 2019 Oct 25. Toxicol In Vitro. 2020. PMID: 31669395 Review.
A Next-Generation Risk Assessment Case Study for Coumarin in Cosmetic Products.
Baltazar MT, Cable S, Carmichael PL, Cubberley R, Cull T, Delagrange M, Dent MP, Hatherell S, Houghton J, Kukic P, Li H, Lee MY, Malcomber S, Middleton AM, Moxon TE, Nathanail AV, Nicol B, Pendlington R, Reynolds G, Reynolds J, White A, Westmoreland C. Baltazar MT, et al. Among authors: carmichael pl. Toxicol Sci. 2020 Jul 1;176(1):236-252. doi: 10.1093/toxsci/kfaa048. Toxicol Sci. 2020. PMID: 32275751 Free PMC article.
Ready for regulatory use: NAMs and NGRA for chemical safety assurance.
Carmichael PL, Baltazar MT, Cable S, Cochrane S, Dent M, Li H, Middleton A, Muller I, Reynolds G, Westmoreland C, White A. Carmichael PL, et al. ALTEX. 2022;39(3):359–366. doi: 10.14573/altex.2204281. Epub 2022 Jul 4. ALTEX. 2022. PMID: 35796331 Free article.
Are Non-animal Systemic Safety Assessments Protective? A Toolbox and Workflow.
Middleton AM, Reynolds J, Cable S, Baltazar MT, Li H, Bevan S, Carmichael PL, Dent MP, Hatherell S, Houghton J, Kukic P, Liddell M, Malcomber S, Nicol B, Park B, Patel H, Scott S, Sparham C, Walker P, White A. Middleton AM, et al. Among authors: carmichael pl. Toxicol Sci. 2022 Aug 25;189(1):124-147. doi: 10.1093/toxsci/kfac068. Toxicol Sci. 2022. PMID: 35822611 Free PMC article.
Beyond AOPs: A Mechanistic Evaluation of NAMs in DART Testing.
Rajagopal R, Baltazar MT, Carmichael PL, Dent MP, Head J, Li H, Muller I, Reynolds J, Sadh K, Simpson W, Spriggs S, White A, Kukic P. Rajagopal R, et al. Among authors: carmichael pl. Front Toxicol. 2022 Mar 7;4:838466. doi: 10.3389/ftox.2022.838466. eCollection 2022. Front Toxicol. 2022. PMID: 35295212 Free PMC article.
Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients.
Dent MP, Vaillancourt E, Thomas RS, Carmichael PL, Ouedraogo G, Kojima H, Barroso J, Ansell J, Barton-Maclaren TS, Bennekou SH, Boekelheide K, Ezendam J, Field J, Fitzpatrick S, Hatao M, Kreiling R, Lorencini M, Mahony C, Montemayor B, Mazaro-Costa R, Oliveira J, Rogiers V, Smegal D, Taalman R, Tokura Y, Verma R, Willett C, Yang C. Dent MP, et al. Among authors: carmichael pl. Regul Toxicol Pharmacol. 2021 Oct;125:105026. doi: 10.1016/j.yrtph.2021.105026. Epub 2021 Aug 10. Regul Toxicol Pharmacol. 2021. PMID: 34389358 Free PMC article.
Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium.
Rusyn I, Sakolish C, Kato Y, Stephan C, Vergara L, Hewitt P, Bhaskaran V, Davis M, Hardwick RN, Ferguson SS, Stanko JP, Bajaj P, Adkins K, Sipes NS, Hunter ES, Baltazar MT, Carmichael PL, Sadh K, Becker RA. Rusyn I, et al. Among authors: carmichael pl. Toxicol Sci. 2022 Jul 28;188(2):143-152. doi: 10.1093/toxsci/kfac061. Toxicol Sci. 2022. PMID: 35689632 Free PMC article.
136 results