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231 results

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Effective drug combinations in breast, colon and pancreatic cancer cells.
Jaaks P, Coker EA, Vis DJ, Edwards O, Carpenter EF, Leto SM, Dwane L, Sassi F, Lightfoot H, Barthorpe S, van der Meer D, Yang W, Beck A, Mironenko T, Hall C, Hall J, Mali I, Richardson L, Tolley C, Morris J, Thomas F, Lleshi E, Aben N, Benes CH, Bertotti A, Trusolino L, Wessels L, Garnett MJ. Jaaks P, et al. Among authors: van der meer d. Nature. 2022 Mar;603(7899):166-173. doi: 10.1038/s41586-022-04437-2. Epub 2022 Feb 23. Nature. 2022. PMID: 35197630 Free PMC article.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ. Behan FM, et al. Among authors: van der meer d. Nature. 2019 Apr;568(7753):511-516. doi: 10.1038/s41586-019-1103-9. Epub 2019 Apr 10. Nature. 2019. PMID: 30971826 Free article.
Integrated cross-study datasets of genetic dependencies in cancer.
Pacini C, Dempster JM, Boyle I, Gonçalves E, Najgebauer H, Karakoc E, van der Meer D, Barthorpe A, Lightfoot H, Jaaks P, McFarland JM, Garnett MJ, Tsherniak A, Iorio F. Pacini C, et al. Among authors: van der meer d. Nat Commun. 2021 Mar 12;12(1):1661. doi: 10.1038/s41467-021-21898-7. Nat Commun. 2021. PMID: 33712601 Free PMC article.
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.
Bashi AC, Coker EA, Bulusu KC, Jaaks P, Crafter C, Lightfoot H, Milo M, McCarten K, Jenkins DF, van der Meer D, Lynch JT, Barthorpe S, Andersen CL, Barry ST, Beck A, Cidado J, Gordon JA, Hall C, Hall J, Mali I, Mironenko T, Mongeon K, Morris J, Richardson L, Smith PD, Tavana O, Tolley C, Thomas F, Willis BS, Yang W, O'Connor MJ, McDermott U, Critchlow SE, Drew L, Fawell SE, Mettetal JT, Garnett MJ. Bashi AC, et al. Among authors: van der meer d. Cancer Discov. 2024 May 1;14(5):846-865. doi: 10.1158/2159-8290.CD-23-0388. Cancer Discov. 2024. PMID: 38456804 Free PMC article.
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets.
Frei O, Hindley G, Shadrin AA, van der Meer D, Akdeniz BC, Hagen E, Cheng W, O'Connell KS, Bahrami S, Parker N, Smeland OB, Holland D; Schizophrenia Working Group of the Psychiatric Genomics Consortium; de Leeuw C, Posthuma D, Andreassen OA, Dale AM. Frei O, et al. Among authors: van der meer d. Nat Genet. 2024 Jun 3. doi: 10.1038/s41588-024-01771-1. Online ahead of print. Nat Genet. 2024. PMID: 38831010
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology.
Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB. Karadag N, et al. Among authors: van der meer d. Neurol Genet. 2024 May 29;10(3):e200143. doi: 10.1212/NXG.0000000000200143. eCollection 2024 Jun. Neurol Genet. 2024. PMID: 38817246 Free PMC article.
Development of a novel non-invasive biomarker panel for hepatic fibrosis in MASLD.
Verschuren L, Mak AL, van Koppen A, Özsezen S, Difrancesco S, Caspers MPM, Snabel J, van der Meer D, van Dijk AM, Rashu EB, Nabilou P, Werge MP, van Son K, Kleemann R, Kiliaan AJ, Hazebroek EJ, Boonstra A, Brouwer WP, Doukas M, Gupta S, Kluft C, Nieuwdorp M, Verheij J, Gluud LL, Holleboom AG, Tushuizen ME, Hanemaaijer R. Verschuren L, et al. Among authors: van der meer d. Nat Commun. 2024 May 29;15(1):4564. doi: 10.1038/s41467-024-48956-0. Nat Commun. 2024. PMID: 38811591 Free PMC article.
231 results