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An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.
Sistare FD, Morton D, Alden C, Christensen J, Keller D, Jonghe SD, Storer RD, Reddy MV, Kraynak A, Trela B, Bienvenu JG, Bjurström S, Bosmans V, Brewster D, Colman K, Dominick M, Evans J, Hailey JR, Kinter L, Liu M, Mahrt C, Marien D, Myer J, Perry R, Potenta D, Roth A, Sherratt P, Singer T, Slim R, Soper K, Fransson-Steen R, Stoltz J, Turner O, Turnquist S, van Heerden M, Woicke J, DeGeorge JJ. Sistare FD, et al. Toxicol Pathol. 2011 Jun;39(4):716-44. doi: 10.1177/0192623311406935. Toxicol Pathol. 2011. PMID: 21666103
An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. I. Evidence for a confounding nonresponder phenotype.
Weaver JL, Contrera JF, Rosenzweig BA, Thompson KL, Faustino PJ, Strong JM, Ellison CD, Anderson LW, Prasanna HR, Long-Bradley PE, Lin KK, Zhang J, Sistare FD. Weaver JL, et al. Among authors: sistare fd. Toxicol Pathol. 1998 Jul-Aug;26(4):532-40. doi: 10.1177/019262339802600409. Toxicol Pathol. 1998. PMID: 9715512
Use of transgenic mice in carcinogenicity hazard assessment.
Jacobson-Kram D, Sistare FD, Jacobs AC. Jacobson-Kram D, et al. Among authors: sistare fd. Toxicol Pathol. 2004 Mar-Apr;32 Suppl 1:49-52. doi: 10.1080/01926230490424761. Toxicol Pathol. 2004. PMID: 15209403 Review.
112 results