D'Orso I - Search Results

1

ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.

Ramirez NP, Lee J, Zheng Y, Li L, Dennis B, Chen D, Challa A, Planelles V, Westover KD, Alto NM, D'Orso I. Ramirez NP, et al. Among authors: d orso i. Nat Commun. 2022 Mar 1;13(1):1109. doi: 10.1038/s41467-022-28772-0. Nat Commun. 2022. PMID: 35232997 Free PMC article.

2

CDK9: a signaling hub for transcriptional control.

Bacon CW, D'Orso I. Bacon CW, et al. Transcription. 2019 Apr;10(2):57-75. doi: 10.1080/21541264.2018.1523668. Epub 2018 Oct 11. Transcription. 2019. PMID: 30227759 Free PMC article. Review.

3

Transcriptional Circuit Fragility Influences HIV Proviral Fate.

Morton EL, Forst CV, Zheng Y, DePaula-Silva AB, Ramirez NP, Planelles V, D'Orso I. Morton EL, et al. Cell Rep. 2019 Apr 2;27(1):154-171.e9. doi: 10.1016/j.celrep.2019.03.007. Cell Rep. 2019. PMID: 30943398 Free PMC article.

4

KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs.

Bacon CW, Challa A, Hyder U, Shukla A, Borkar AN, Bayo J, Liu J, Wu SY, Chiang CM, Kutateladze TG, D'Orso I. Bacon CW, et al. Mol Cell. 2020 Jun 18;78(6):1133-1151.e14. doi: 10.1016/j.molcel.2020.04.024. Epub 2020 May 12. Mol Cell. 2020. PMID: 32402252 Free PMC article.

5

HIV-1 Proviral Transcription and Latency in the New Era.

Shukla A, Ramirez NP, D'Orso I. Shukla A, et al. Viruses. 2020 May 18;12(5):555. doi: 10.3390/v12050555. Viruses. 2020. PMID: 32443452 Free PMC article. Review.

6

Cleavage and Polyadenylation Specificity Factor 6 Is Required for Efficient HIV-1 Latency Reversal.

Zheng Y, Schubert HL, Singh PK, Martins LJ, Engelman AN, D'Orso I, Hill CP, Planelles V. Zheng Y, et al. mBio. 2021 Jun 29;12(3):e0109821. doi: 10.1128/mBio.01098-21. Epub 2021 Jun 22. mBio. 2021. PMID: 34154414 Free PMC article.

7

Decoding Human Genome Regulatory Features That Influence HIV-1 Proviral Expression and Fate Through an Integrated Genomics Approach.

Ruess H, Lee J, Guzman C, Malladi VS, D'Orso I. Ruess H, et al. Among authors: d orso i. Bioinform Biol Insights. 2022 Feb 26;16:11779322211072333. doi: 10.1177/11779322211072333. eCollection 2022. Bioinform Biol Insights. 2022. PMID: 35250265 Free PMC article.

8

Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity.

Cruz-Lorenzo E, Ramirez NP, Lee J, Pandhe S, Wang L, Hernandez-Doria J, Spivak AM, Planelles V, Petersen T, Jain MK, Martinez ED, D'Orso I. Cruz-Lorenzo E, et al. Among authors: d orso i. Viruses. 2022 Oct 18;14(10):2288. doi: 10.3390/v14102288. Viruses. 2022. PMID: 36298843 Free PMC article.

9

The PNUTS-PP1 complex acts as an intrinsic barrier to herpesvirus KSHV gene expression and replication.

Devlin AM, Shukla A, Ruiz JC, Barnes SD, Govindan A, Hunter OV, Scarborough AM, D'Orso I, Conrad NK. Devlin AM, et al. Among authors: d orso i. Nat Commun. 2022 Dec 2;13(1):7447. doi: 10.1038/s41467-022-35268-4. Nat Commun. 2022. PMID: 36460671 Free PMC article.

10

Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation.

Randolph K, Hyder U, Challa A, Perez E, D'Orso I. Randolph K, et al. Among authors: d orso i. Viruses. 2024 Jan 13;16(1):116. doi: 10.3390/v16010116. Viruses. 2024. PMID: 38257816 Free PMC article.

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