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NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats.
Elife. 2022 Mar 2;11:e72468. doi: 10.7554/eLife.72468.
Elife. 2022.
PMID: 35234610
Free PMC article.
Clinical characteristics and treatment experience of individuals with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE): Findings from an online caregiver survey.
Cutts A, Savoie H, Hammer MF, Schreiber J, Grayson C, Luzon C, Butterfield N, Pimstone SN, Aycardi E, Harden C, Yonan C, Jen E, Nguyen T, Carmack T, Haubenberger D.
Cutts A, et al.
Seizure. 2022 Apr;97:50-57. doi: 10.1016/j.seizure.2022.03.008. Epub 2022 Mar 10.
Seizure. 2022.
PMID: 35325842
Free article.
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Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.
Cutts A, Chowdhury S, Ratkay LG, Eyers M, Young C, Namdari R, Cadieux JA, Chahal N, Grimwood M, Zhang Z, Lin S, Tietjen I, Xie Z, Robinette L, Sojo L, Waldbrook M, Hayden M, Mansour T, Pimstone S, Goldberg YP, Webb M, Cohen CJ.
Cutts A, et al.
J Pharmacol Exp Ther. 2023 Jul;386(1):4-14. doi: 10.1124/jpet.122.001435. Epub 2023 Mar 23.
J Pharmacol Exp Ther. 2023.
PMID: 36958846
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Early phase TGFβ receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses.
Cutts AJ, Soond SM, Powell S, Chantry A.
Cutts AJ, et al.
Int J Biochem Cell Biol. 2011 Apr;43(4):604-12. doi: 10.1016/j.biocel.2010.12.018. Epub 2010 Dec 25.
Int J Biochem Cell Biol. 2011.
PMID: 21187158
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Deficits of [3H]D-aspartate binding to glutamate uptake sites in striatal and accumbens tissue in patients with schizophrenia.
Aparicio-Legarza MI, Cutts AJ, Davis B, Reynolds GP.
Aparicio-Legarza MI, et al. Among authors: cutts aj.
Neurosci Lett. 1997 Aug 22;232(1):13-6. doi: 10.1016/s0304-3940(97)00563-6.
Neurosci Lett. 1997.
PMID: 9292880
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Free radical damage in Down's syndrome brain.
Reynolds GP, Cutts AJ.
Reynolds GP, et al. Among authors: cutts aj.
Biochem Soc Trans. 1993 May;21(2):221S. doi: 10.1042/bst021221s.
Biochem Soc Trans. 1993.
PMID: 8359470
No abstract available.
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D-aspartate binding to the glutamate uptake site in human brain tissue--effects of leucotomy.
Cutts AJ, Reynolds GP.
Cutts AJ, et al.
J Neural Transm Gen Sect. 1993;94(2):147-52. doi: 10.1007/BF01245008.
J Neural Transm Gen Sect. 1993.
PMID: 8110441
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