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Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue.
Budelmann D, Laue H, Weiss N, Dahmen U, D'Alessandro LA, Biermayer I, Klingmüller U, Ghallab A, Hassan R, Begher-Tibbe B, Hengstler JG, Schwen LO. Budelmann D, et al. Among authors: klingmuller u. J Pathol Inform. 2022 Jan 20;13:100001. doi: 10.1016/j.jpi.2022.100001. eCollection 2022. J Pathol Inform. 2022. PMID: 35242441 Free PMC article.
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice.
Castoldi M, Vujic Spasic M, Altamura S, Elmén J, Lindow M, Kiss J, Stolte J, Sparla R, D'Alessandro LA, Klingmüller U, Fleming RE, Longerich T, Gröne HJ, Benes V, Kauppinen S, Hentze MW, Muckenthaler MU. Castoldi M, et al. Among authors: klingmuller u. J Clin Invest. 2011 Apr;121(4):1386-96. doi: 10.1172/JCI44883. J Clin Invest. 2011. PMID: 21364282 Free PMC article.
Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration.
Meyer R, D'Alessandro LA, Kar S, Kramer B, She B, Kaschek D, Hahn B, Wrangborg D, Karlsson J, Kvarnström M, Jirstrand M, Lehmann WD, Timmer J, Höfer T, Klingmüller U. Meyer R, et al. Among authors: klingmuller u. Front Physiol. 2012 Nov 28;3:451. doi: 10.3389/fphys.2012.00451. eCollection 2012. Front Physiol. 2012. PMID: 23226133 Free PMC article.
Hepatocellular carcinoma: a systems biology perspective.
D'Alessandro LA, Meyer R, Klingmüller U. D'Alessandro LA, et al. Among authors: klingmuller u. Front Physiol. 2013 Feb 25;4:28. doi: 10.3389/fphys.2013.00028. eCollection 2013. Front Physiol. 2013. PMID: 23444340 Free PMC article.
The virtual liver: state of the art and future perspectives.
Drasdo D, Bode J, Dahmen U, Dirsch O, Dooley S, Gebhardt R, Ghallab A, Godoy P, Häussinger D, Hammad S, Hoehme S, Holzhütter HG, Klingmüller U, Kuepfer L, Timmer J, Zerial M, Hengstler JG. Drasdo D, et al. Among authors: klingmuller u. Arch Toxicol. 2014 Dec;88(12):2071-5. doi: 10.1007/s00204-014-1384-6. Arch Toxicol. 2014. PMID: 25331938 No abstract available.
Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling.
D'Alessandro LA, Samaga R, Maiwald T, Rho SH, Bonefas S, Raue A, Iwamoto N, Kienast A, Waldow K, Meyer R, Schilling M, Timmer J, Klamt S, Klingmüller U. D'Alessandro LA, et al. Among authors: klingmuller u. PLoS Comput Biol. 2015 Apr 23;11(4):e1004192. doi: 10.1371/journal.pcbi.1004192. eCollection 2015 Apr. PLoS Comput Biol. 2015. PMID: 25905717 Free PMC article.
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.
Sobotta S, Raue A, Huang X, Vanlier J, Jünger A, Bohl S, Albrecht U, Hahnel MJ, Wolf S, Mueller NS, D'Alessandro LA, Mueller-Bohl S, Boehm ME, Lucarelli P, Bonefas S, Damm G, Seehofer D, Lehmann WD, Rose-John S, van der Hoeven F, Gretz N, Theis FJ, Ehlting C, Bode JG, Timmer J, Schilling M, Klingmüller U. Sobotta S, et al. Among authors: klingmuller u. Front Physiol. 2017 Oct 9;8:775. doi: 10.3389/fphys.2017.00775. eCollection 2017. Front Physiol. 2017. PMID: 29062282 Free PMC article.
133 results