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Architecture and hydration of the arginine-binding site of neuropilin-1.
Mota F, Fotinou C, Rana RR, Chan AWE, Yelland T, Arooz MT, O'Leary AP, Hutton J, Frankel P, Zachary I, Selwood D, Djordjevic S. Mota F, et al. FEBS J. 2018 Apr;285(7):1290-1304. doi: 10.1111/febs.14405. Epub 2018 Feb 25. FEBS J. 2018. PMID: 29430837 Free PMC article.
Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells.
Powell J, Mota F, Steadman D, Soudy C, Miyauchi JT, Crosby S, Jarvis A, Reisinger T, Winfield N, Evans G, Finniear A, Yelland T, Chou YT, Chan AWE, O'Leary A, Cheng L, Liu D, Fotinou C, Milagre C, Martin JF, Jia H, Frankel P, Djordjevic S, Tsirka SE, Zachary IC, Selwood DL. Powell J, et al. Among authors: mota f. J Med Chem. 2018 May 10;61(9):4135-4154. doi: 10.1021/acs.jmedchem.8b00210. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29648813 Free PMC article.
A new small molecule inhibitor of soluble guanylate cyclase.
Mota F, Gane P, Hampden-Smith K, Allerston CK, Garthwaite J, Selwood DL. Mota F, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5303-10. doi: 10.1016/j.bmc.2015.07.074. Epub 2015 Aug 4. Bioorg Med Chem. 2015. PMID: 26264842 Free PMC article.
Endothelial C-type natriuretic peptide maintains vascular homeostasis.
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock AS, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A, Hobbs AJ. Moyes AJ, et al. Among authors: mota f. J Clin Invest. 2014 Sep;124(9):4039-51. doi: 10.1172/JCI74281. Epub 2014 Aug 8. J Clin Invest. 2014. PMID: 25105365 Free PMC article.
Radiotracer Development for Bacterial Imaging.
Mota F, Ordonez AA, Firth G, Ruiz-Bedoya CA, Ma MT, Jain SK. Mota F, et al. J Med Chem. 2020 Mar 12;63(5):1964-1977. doi: 10.1021/acs.jmedchem.9b01623. Epub 2020 Feb 21. J Med Chem. 2020. PMID: 32048838 Free PMC article. Review.
286 results