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Convergent selective signaling impairment exposes the pathogenicity of latrophilin-3 missense variants linked to inheritable ADHD susceptibility.
Moreno-Salinas AL, Holleran BJ, Ojeda-Muñiz EY, Correoso-Braña KG, Ribalta-Mena S, Ovando-Zambrano JC, Leduc R, Boucard AA. Moreno-Salinas AL, et al. Among authors: holleran bj. Mol Psychiatry. 2022 May;27(5):2425-2438. doi: 10.1038/s41380-022-01537-3. Epub 2022 Apr 7. Mol Psychiatry. 2022. PMID: 35393556 Free PMC article.
The second transmembrane domain of the human type 1 angiotensin II receptor participates in the formation of the ligand binding pocket and undergoes integral pivoting movement during the process of receptor activation.
Domazet I, Holleran BJ, Martin SS, Lavigne P, Leduc R, Escher E, Guillemette G. Domazet I, et al. Among authors: holleran bj. J Biol Chem. 2009 May 1;284(18):11922-9. doi: 10.1074/jbc.M808113200. Epub 2009 Mar 9. J Biol Chem. 2009. PMID: 19276075 Free PMC article.
The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation.
Domazet I, Martin SS, Holleran BJ, Morin ME, Lacasse P, Lavigne P, Escher E, Leduc R, Guillemette G. Domazet I, et al. Among authors: holleran bj. J Biol Chem. 2009 Nov 13;284(46):31953-61. doi: 10.1074/jbc.M109.051839. Epub 2009 Sep 22. J Biol Chem. 2009. PMID: 19773549 Free PMC article.
28 results