Díaz JF - Search Results

1

Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function.

Oliva MÁ, Tosat-Bitrián C, Barrado-Gil L, Bonato F, Galindo I, Garaigorta U, Álvarez-Bernad B, París-Ogáyar R, Lucena-Agell D, Giménez-Abián JF, García-Dorival I, Urquiza J, Gastaminza P, Díaz JF, Palomo V, Alonso C. Oliva MÁ, et al. Among authors: diaz jf. Int J Mol Sci. 2022 Mar 22;23(7):3448. doi: 10.3390/ijms23073448. Int J Mol Sci. 2022. PMID: 35408808 Free PMC article.

2

Characterizing ligand-microtubule binding by competition methods.

Díaz JF, Buey RM. Díaz JF, et al. Methods Mol Med. 2007;137:245-60. doi: 10.1007/978-1-59745-442-1_17. Methods Mol Med. 2007. PMID: 18085234

3

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.

Prota AE, Bargsten K, Diaz JF, Marsh M, Cuevas C, Liniger M, Neuhaus C, Andreu JM, Altmann KH, Steinmetz MO. Prota AE, et al. Among authors: diaz jf. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13817-21. doi: 10.1073/pnas.1408124111. Epub 2014 Aug 11. Proc Natl Acad Sci U S A. 2014. PMID: 25114240 Free PMC article.

4

Total Synthesis of Amphidinolide K, a Macrolide That Stabilizes F-Actin.

Sánchez D, Andreou T, Costa AM, Meyer KG, Williams DR, Barasoain I, Díaz JF, Lucena-Agell D, Vilarrasa J. Sánchez D, et al. Among authors: diaz jf. J Org Chem. 2015 Sep 4;80(17):8511-9. doi: 10.1021/acs.joc.5b00966. Epub 2015 Jun 23. J Org Chem. 2015. PMID: 26079383

5

Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation.

Prota AE, Setter J, Waight AB, Bargsten K, Murga J, Diaz JF, Steinmetz MO. Prota AE, et al. Among authors: diaz jf. J Mol Biol. 2016 Jul 31;428(15):2981-8. doi: 10.1016/j.jmb.2016.06.023. Epub 2016 Jul 6. J Mol Biol. 2016. PMID: 27395016 Free article.

6

Aggregated Compound Biological Signatures Facilitate Phenotypic Drug Discovery and Target Elucidation.

Cortes Cabrera A, Lucena-Agell D, Redondo-Horcajo M, Barasoain I, Díaz JF, Fasching B, Petrone PM. Cortes Cabrera A, et al. Among authors: diaz jf. ACS Chem Biol. 2016 Nov 18;11(11):3024-3034. doi: 10.1021/acschembio.6b00358. Epub 2016 Sep 14. ACS Chem Biol. 2016. PMID: 27564241

7

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.

Kellogg EH, Hejab NMA, Howes S, Northcote P, Miller JH, Díaz JF, Downing KH, Nogales E. Kellogg EH, et al. Among authors: diaz jf. J Mol Biol. 2017 Mar 10;429(5):633-646. doi: 10.1016/j.jmb.2017.01.001. Epub 2017 Jan 17. J Mol Biol. 2017. PMID: 28104363 Free PMC article.

8

Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.

Field JJ, Northcote PT, Paterson I, Altmann KH, Díaz JF, Miller JH. Field JJ, et al. Among authors: diaz jf. Int J Mol Sci. 2017 May 3;18(5):971. doi: 10.3390/ijms18050971. Int J Mol Sci. 2017. PMID: 28467385 Free PMC article.

9

Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.

Tang Y, Rodríguez-Salarichs J, Zhao Y, Cai P, Estévez-Gallego J, Balaguer-Pérez F, Redondo Horcajo M, Lucena-Agell D, Barasoain I, Díaz JF, Fang WS. Tang Y, et al. Among authors: diaz jf. Eur J Med Chem. 2017 Sep 8;137:488-503. doi: 10.1016/j.ejmech.2017.06.001. Epub 2017 Jun 3. Eur J Med Chem. 2017. PMID: 28624703

10

Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin.

Sharma A, Sáez-Calvo G, Olieric N, de Asís Balaguer F, Barasoain I, Lamberth C, Díaz JF, Steinmetz MO. Sharma A, et al. Among authors: diaz jf. Int J Mol Sci. 2017 Jun 22;18(7):1336. doi: 10.3390/ijms18071336. Int J Mol Sci. 2017. PMID: 28640209 Free PMC article.

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