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Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients.
Sperry MM, Oskotsky T, MariÄ I, Kaushal S, Takeda T, Horvath V, Powers RK, Rodas M, Furlong B, Soong M, Prabhala P, Goyal G, Carlson KE, Wong RJ, Kosti I, Le BL, Logue J, Hammond H, Frieman M, Stevenson DK, Ingber DE, Sirota M, Novak R. Sperry MM, et al. Among authors: logue j. medRxiv [Preprint]. 2022 Jul 22:2022.04.12.22273802. doi: 10.1101/2022.04.12.22273802. medRxiv. 2022. Update in: PLoS Comput Biol. 2023 May 5;19(5):e1011050. doi: 10.1371/journal.pcbi.1011050. PMID: 35441166 Free PMC article. Updated. Preprint.
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.
Si L, Bai H, Rodas M, Cao W, Oh CY, Jiang A, Moller R, Hoagland D, Oishi K, Horiuchi S, Uhl S, Blanco-Melo D, Albrecht RA, Liu WC, Jordan T, Nilsson-Payant BE, Golynker I, Frere J, Logue J, Haupt R, McGrath M, Weston S, Zhang T, Plebani R, Soong M, Nurani A, Kim SM, Zhu DY, Benam KH, Goyal G, Gilpin SE, Prantil-Baun R, Gygi SP, Powers RK, Carlson KE, Frieman M, tenOever BR, Ingber DE. Si L, et al. Among authors: logue j. Nat Biomed Eng. 2021 Aug;5(8):815-829. doi: 10.1038/s41551-021-00718-9. Epub 2021 May 3. Nat Biomed Eng. 2021. PMID: 33941899 Free PMC article.
Self-assembling short immunostimulatory duplex RNAs with broad spectrum antiviral activity.
Si L, Bai H, Oh CY, Zhang T, Hong F, Jiang A, Ye Y, Jordan TX, Logue J, McGrath M, Belgur C, Nurani A, Cao W, Prantil-Baun R, Gygi SP, Powers RK, Frieman M, tenOever BR, Ingber DE. Si L, et al. Among authors: logue j. bioRxiv [Preprint]. 2021 Nov 22:2021.11.19.469183. doi: 10.1101/2021.11.19.469183. bioRxiv. 2021. Update in: Mol Ther Nucleic Acids. 2022 Sep 13;29:923-940. doi: 10.1016/j.omtn.2022.08.031. PMID: 34845453 Free PMC article. Updated. Preprint.
PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19.
Logue J, Chakraborty AR, Johnson R, Goyal G, Rodas M, Taylor LJ, Baracco L, McGrath ME, Haupt R, Furlong BA, Soong M, Prabhala P, Horvath V, Carlson KE, Weston S, Ingber DE, DePamphilis ML, Frieman MB. Logue J, et al. Commun Biol. 2022 Aug 12;5(1):808. doi: 10.1038/s42003-022-03766-2. Commun Biol. 2022. PMID: 35962188 Free PMC article.
Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity.
Si L, Bai H, Oh CY, Jiang A, Hong F, Zhang T, Ye Y, Jordan TX, Logue J, McGrath M, Belgur C, Calderon K, Nurani A, Cao W, Carlson KE, Prantil-Baun R, Gygi SP, Yang D, Jonsson CB, tenOever BR, Frieman M, Ingber DE. Si L, et al. Among authors: logue j. Mol Ther Nucleic Acids. 2022 Sep 13;29:923-940. doi: 10.1016/j.omtn.2022.08.031. Epub 2022 Aug 24. Mol Ther Nucleic Acids. 2022. PMID: 36032397 Free PMC article.
Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients.
Sperry MM, Oskotsky TT, Marić I, Kaushal S, Takeda T, Horvath V, Powers RK, Rodas M, Furlong B, Soong M, Prabhala P, Goyal G, Carlson KE, Wong RJ, Kosti I, Le BL, Logue J, Hammond H, Frieman M, Stevenson DK, Ingber DE, Sirota M, Novak R. Sperry MM, et al. Among authors: logue j. PLoS Comput Biol. 2023 May 5;19(5):e1011050. doi: 10.1371/journal.pcbi.1011050. eCollection 2023 May. PLoS Comput Biol. 2023. PMID: 37146076 Free PMC article.
430 results