He Z - Search Results

1

Advances and challenges in quantitative delineation of the genetic architecture of complex traits.

Tang H, He Z. Tang H, et al. Among authors: he z. Quant Biol. 2021 Jun;9(2):168-184. doi: 10.15302/j-qb-021-0249. Quant Biol. 2021. PMID: 35492964 Free PMC article.

2

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.

He Z, Liu L, Wang C, Le Guen Y, Lee J, Gogarten S, Lu F, Montgomery S, Tang H, Silverman EK, Cho MH, Greicius M, Ionita-Laza I. He Z, et al. Nat Commun. 2021 May 25;12(1):3152. doi: 10.1038/s41467-021-22889-4. Nat Commun. 2021. PMID: 34035245 Free PMC article.

3

Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics.

He Z, Le Guen Y, Liu L, Lee J, Ma S, Yang AC, Liu X, Rutledge J, Losada PM, Song B, Belloy ME, Butler RR 3rd, Longo FM, Tang H, Mormino EC, Wyss-Coray T, Greicius MD, Ionita-Laza I. He Z, et al. Am J Hum Genet. 2021 Dec 2;108(12):2336-2353. doi: 10.1016/j.ajhg.2021.10.009. Epub 2021 Nov 11. Am J Hum Genet. 2021. PMID: 34767756 Free PMC article.

4

GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies.

He Z, Liu L, Belloy ME, Le Guen Y, Sossin A, Liu X, Qi X, Ma S, Gyawali PK, Wyss-Coray T, Tang H, Sabatti C, Candès E, Greicius MD, Ionita-Laza I. He Z, et al. Nat Commun. 2022 Nov 23;13(1):7209. doi: 10.1038/s41467-022-34932-z. Nat Commun. 2022. PMID: 36418338 Free PMC article.

5

Improving genetic risk prediction across diverse population by disentangling ancestry representations.

Gyawali PK, Le Guen Y, Liu X, Belloy ME, Tang H, Zou J, He Z. Gyawali PK, et al. Among authors: he z. Commun Biol. 2023 Sep 22;6(1):964. doi: 10.1038/s42003-023-05352-6. Commun Biol. 2023. PMID: 37736834 Free PMC article.

6

Beyond guilty by association at scale: searching for causal variants on the basis of genome-wide summary statistics.

He Z, Chu B, Yang J, Gu J, Chen Z, Liu L, Morrison T, Belloy ME, Qi X, Hejazi N, Mathur M, Le Guen Y, Tang H, Hastie T, Ionita-Laza I, Sabatti C, Candès E. He Z, et al. bioRxiv [Preprint]. 2024 May 2:2024.02.28.582621. doi: 10.1101/2024.02.28.582621. bioRxiv. 2024. PMID: 38464202 Free PMC article. Preprint.

7

Quantitative disease risk scores from EHR with applications to clinical risk stratification and genetic studies.

Xu D, Wang C, Khan A, Shang N, He Z, Gordon A, Kullo IJ, Murphy S, Ni Y, Wei WQ, Gharavi A, Kiryluk K, Weng C, Ionita-Laza I. Xu D, et al. Among authors: he z. NPJ Digit Med. 2021 Jul 23;4(1):116. doi: 10.1038/s41746-021-00488-3. NPJ Digit Med. 2021. PMID: 34302027 Free PMC article.

8

Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping.

Belloy ME, Eger SJ, Le Guen Y, Damotte V, Ahmad S, Ikram MA, Ramirez A, Tsolaki AC, Rossi G, Jansen IE, de Rojas I, Parveen K, Sleegers K, Ingelsson M, Hiltunen M, Amin N, Andreassen O, Sánchez-Juan P, Kehoe P, Amouyel P, Sims R, Frikke-Schmidt R, van der Flier WM, Lambert JC; European Alzheimer & Dementia BioBank (EADB); He Z, Han SS, Napolioni V, Greicius MD. Belloy ME, et al. Among authors: he z. Alzheimers Res Ther. 2022 Feb 4;14(1):22. doi: 10.1186/s13195-022-00962-4. Alzheimers Res Ther. 2022. PMID: 35120553 Free PMC article.

9

Multiple causal variants underlie genetic associations in humans.

Abell NS, DeGorter MK, Gloudemans MJ, Greenwald E, Smith KS, He Z, Montgomery SB. Abell NS, et al. Among authors: he z. Science. 2022 Mar 18;375(6586):1247-1254. doi: 10.1126/science.abj5117. Epub 2022 Mar 17. Science. 2022. PMID: 35298243 Free PMC article.

10

Deep neural networks with controlled variable selection for the identification of putative causal genetic variants.

Kassani PH, Lu F, Guen YL, Belloy ME, He Z. Kassani PH, et al. Among authors: he z. Nat Mach Intell. 2022 Sep;4(9):761-771. doi: 10.1038/s42256-022-00525-0. Epub 2022 Sep 15. Nat Mach Intell. 2022. PMID: 37859729 Free PMC article.

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