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Navitoclax safety, tolerability, and effect on biomarkers of senescence and neurodegeneration in aged nonhuman primates.
Greenberg EF, Voorbach MJ, Smith A, Reuter DR, Zhuang Y, Wang JQ, Wooten DW, Asque E, Hu M, Hoft C, Duggan R, Townsend M, Orsi K, Dalecki K, Amberg W, Duggan L, Knight H, Spina JS, He Y, Marsh K, Zhao V, Ybarra S, Mollon J, Fang Y, Vasanthakumar A, Westmoreland S, Droescher M, Finnema SJ, Florian H. Greenberg EF, et al. Among authors: knight h. Heliyon. 2024 Aug 17;10(16):e36483. doi: 10.1016/j.heliyon.2024.e36483. eCollection 2024 Aug 30. Heliyon. 2024. PMID: 39253182 Free PMC article.
Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1β Secretion and T Cell Adjuvanticity.
Weiss AM, Lopez MA 2nd, Rosenberger MG, Kim JY, Shen J, Chen Q, Ung T, Ibeh UM, Knight HR, Rutledge NS, Studnitzer B, Rowan SJ, Esser-Kahn AP. Weiss AM, et al. Among authors: knight hr. J Med Chem. 2024 Sep 12;67(17):14974-14985. doi: 10.1021/acs.jmedchem.4c00516. Epub 2024 Aug 20. J Med Chem. 2024. PMID: 39162654
418 results