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The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma.
Carvalho A, Cunha C, Almeida AJ, Osório NS, Saraiva M, Teixeira-Coelho M, Pedreiro S, Torrado E, Domingues N, Gomes-Alves AG, Marques A, Lacerda JF, da Silva MG, Gomes M, Pinto AC, Torres F, Rendeiro P, Tavares P, Di Ianni M, Medeiros R, Heutink P, Bracci PM, Conde L, Ludovico P, Pedrosa J, Maciel P, Pitzurra L, Aversa F, Marques H, Paiva A, Skibola CF, Romani L, Castro AG, Rodrigues F. Carvalho A, et al. Among authors: lacerda jf. Genes Immun. 2012 Feb;13(2):197-201. doi: 10.1038/gene.2011.59. Epub 2011 Aug 25. Genes Immun. 2012. PMID: 21866115 Free PMC article.
Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation.
Cunha C, Aversa F, Lacerda JF, Busca A, Kurzai O, Grube M, Löffler J, Maertens JA, Bell AS, Inforzato A, Barbati E, Almeida B, Santos e Sousa P, Barbui A, Potenza L, Caira M, Rodrigues F, Salvatori G, Pagano L, Luppi M, Mantovani A, Velardi A, Romani L, Carvalho A. Cunha C, et al. Among authors: lacerda jf. N Engl J Med. 2014 Jan 30;370(5):421-32. doi: 10.1056/NEJMoa1211161. N Engl J Med. 2014. PMID: 24476432 Free article.
The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells.
Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR, Cassis L, Carrillo J, Puga I, Cunha C, Bastos H, Rodrigues F, Lacerda JF, Morais A, Dieguez-Gonzalez R, Heeger PS, Salvatori G, Carvalho A, Garcia-Sastre A, Blander JM, Mantovani A, Garlanda C, Cerutti A. Chorny A, et al. Among authors: lacerda jf. J Exp Med. 2016 Sep 19;213(10):2167-85. doi: 10.1084/jem.20150282. Epub 2016 Sep 12. J Exp Med. 2016. PMID: 27621420 Free PMC article.
IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity.
Cunha C, Gonçalves SM, Duarte-Oliveira C, Leite L, Lagrou K, Marques A, Lupiañez CB, Mesquita I, Gaifem J, Barbosa AM, Pinho Vaz C, Branca R, Campilho F, Freitas F, Ligeiro D, Lass-Flörl C, Löffler J, Jurado M, Saraiva M, Kurzai O, Rodrigues F, Castro AG, Silvestre R, Sainz J, Maertens JA, Torrado E, Jacobsen ID, Lacerda JF, Campos A Jr, Carvalho A. Cunha C, et al. Among authors: lacerda jf. J Allergy Clin Immunol. 2017 Sep;140(3):867-870.e9. doi: 10.1016/j.jaci.2017.02.034. Epub 2017 Apr 4. J Allergy Clin Immunol. 2017. PMID: 28389392 Free article. No abstract available.
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus.
Stappers MHT, Clark AE, Aimanianda V, Bidula S, Reid DM, Asamaphan P, Hardison SE, Dambuza IM, Valsecchi I, Kerscher B, Plato A, Wallace CA, Yuecel R, Hebecker B, da Glória Teixeira Sousa M, Cunha C, Liu Y, Feizi T, Brakhage AA, Kwon-Chung KJ, Gow NAR, Zanda M, Piras M, Zanato C, Jaeger M, Netea MG, van de Veerdonk FL, Lacerda JF, Campos A, Carvalho A, Willment JA, Latgé JP, Brown GD. Stappers MHT, et al. Among authors: lacerda jf. Nature. 2018 Mar 15;555(7696):382-386. doi: 10.1038/nature25974. Epub 2018 Feb 28. Nature. 2018. PMID: 29489751 Free PMC article.
Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis.
Kyrmizi I, Ferreira H, Carvalho A, Figueroa JAL, Zarmpas P, Cunha C, Akoumianaki T, Stylianou K, Deepe GS Jr, Samonis G, Lacerda JF, Campos A Jr, Kontoyiannis DP, Mihalopoulos N, Kwon-Chung KJ, El-Benna J, Valsecchi I, Beauvais A, Brakhage AA, Neves NM, Latge JP, Chamilos G. Kyrmizi I, et al. Among authors: lacerda jf. Nat Microbiol. 2018 Jul;3(7):791-803. doi: 10.1038/s41564-018-0167-x. Epub 2018 May 30. Nat Microbiol. 2018. PMID: 29849062
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.
Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A Jr, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL. Gresnigt MS, et al. Among authors: lacerda jf. Nat Commun. 2018 Jul 6;9(1):2636. doi: 10.1038/s41467-018-04912-3. Nat Commun. 2018. PMID: 29980664 Free PMC article.
PTX3 Polymorphisms Influence Cytomegalovirus Reactivation After Stem-Cell Transplantation.
Campos CF, Leite L, Pereira P, Vaz CP, Branca R, Campilho F, Freitas F, Ligeiro D, Marques A, Torrado E, Silvestre R, Lacerda JF, Campos A Jr, Cunha C, Carvalho A. Campos CF, et al. Among authors: lacerda jf. Front Immunol. 2019 Jan 31;10:88. doi: 10.3389/fimmu.2019.00088. eCollection 2019. Front Immunol. 2019. PMID: 30766534 Free PMC article.
75 results