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HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.
Alem F, Brahms A, Tarasaki K, Omole S, Kehn-Hall K, Schmaljohn CS, Bavari S, Makino S, Hakami RM. Alem F, et al. Among authors: bavari s. Front Cell Infect Microbiol. 2024 May 10;14:1331755. doi: 10.3389/fcimb.2024.1331755. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38800833 Free PMC article.
Immunogenicity and Efficacy of TNX-1800, A Live Virus Recombinant Poxvirus Vaccine Candidate, against SARS-CoV-2 Challenge in Nonhuman Primates.
Awasthi M, Macaluso A, Myscofski D, Prigge J, Koide F, Noyce RS, Fogarty S, Stillwell H, Goebel SJ, Daugherty B, Nasar F, Bavari S, Lederman S. Awasthi M, et al. Among authors: bavari s. Vaccines (Basel). 2023 Nov 2;11(11):1682. doi: 10.3390/vaccines11111682. Vaccines (Basel). 2023. PMID: 38006014 Free PMC article.
Development of a rapid image-based high-content imaging screening assay to evaluate therapeutic antibodies against the monkeypox virus.
Kota KP, Ziółkowska NE, Wei J, Peng J, Ordonez D, Raney C, Prigge J, Hooper JW, Awasthi M, Goebel SJ, Zabel BA, Nasar F, Lederman S, Bavari S. Kota KP, et al. Among authors: bavari s. Antiviral Res. 2023 Feb;210:105513. doi: 10.1016/j.antiviral.2022.105513. Epub 2022 Dec 30. Antiviral Res. 2023. PMID: 36592670 Free PMC article.
Eastern equine encephalitis virus rapidly infects and disseminates in the brain and spinal cord of cynomolgus macaques following aerosol challenge.
Williams JA, Long SY, Zeng X, Kuehl K, Babka AM, Davis NM, Liu J, Trefry JC, Daye S, Facemire PR, Iversen PL, Bavari S, Pitt ML, Nasar F. Williams JA, et al. Among authors: bavari s. PLoS Negl Trop Dis. 2022 May 9;16(5):e0010081. doi: 10.1371/journal.pntd.0010081. eCollection 2022 May. PLoS Negl Trop Dis. 2022. PMID: 35533188 Free PMC article.
A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With Bacillus anthracis.
Chiang CY, Lane DJ, Zou Y, Hoffman T, Pan J, Hampton J, Maginnis J, Nayak BP, D'Oro U, Valiante N, Miller AT, Cooke M, Wu T, Bavari S, Panchal RG. Chiang CY, et al. Among authors: bavari s. Front Microbiol. 2022 Mar 14;13:803041. doi: 10.3389/fmicb.2022.803041. eCollection 2022. Front Microbiol. 2022. PMID: 35369443 Free PMC article.
Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy.
Alem F, Olanrewaju AA, Omole S, Hobbs HE, Ahsan N, Matulis G, Brantner CA, Zhou W, Petricoin EF, Liotta LA, Caputi M, Bavari S, Wu Y, Kashanchi F, Hakami RM. Alem F, et al. Among authors: bavari s. Cell Biosci. 2021 Dec 25;11(1):220. doi: 10.1186/s13578-021-00732-z. Cell Biosci. 2021. PMID: 34953502 Free PMC article.
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