Ali A - Search Results

1

Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition.

Arya R, Maben Z, Rane D, Ali A, Stern LJ. Arya R, et al. Among authors: ali a. ACS Chem Biol. 2022 Jul 15;17(7):1756-1768. doi: 10.1021/acschembio.2c00093. Epub 2022 Jun 29. ACS Chem Biol. 2022. PMID: 35767698

2

Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance.

Ali A, Aydin C, Gildemeister R, Romano KP, Cao H, Ozen A, Soumana D, Newton A, Petropoulos CJ, Huang W, Schiffer CA. Ali A, et al. ACS Chem Biol. 2013 Jul 19;8(7):1469-78. doi: 10.1021/cb400100g. Epub 2013 May 1. ACS Chem Biol. 2013. PMID: 23594083 Free PMC article.

3

Structural analysis of asunaprevir resistance in HCV NS3/4A protease.

Soumana DI, Ali A, Schiffer CA. Soumana DI, et al. Among authors: ali a. ACS Chem Biol. 2014 Nov 21;9(11):2485-90. doi: 10.1021/cb5006118. Epub 2014 Sep 30. ACS Chem Biol. 2014. PMID: 25243902 Free PMC article.

4

Simultaneously Targeting the NS3 Protease and Helicase Activities for More Effective Hepatitis C Virus Therapy.

Ndjomou J, Corby MJ, Sweeney NL, Hanson AM, Aydin C, Ali A, Schiffer CA, Li K, Frankowski KJ, Schoenen FJ, Frick DN. Ndjomou J, et al. Among authors: ali a. ACS Chem Biol. 2015 Aug 21;10(8):1887-96. doi: 10.1021/acschembio.5b00101. Epub 2015 May 22. ACS Chem Biol. 2015. PMID: 25961497 Free PMC article.

5

Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172.

Soumana DI, Kurt Yilmaz N, Prachanronarong KL, Aydin C, Ali A, Schiffer CA. Soumana DI, et al. Among authors: ali a. ACS Chem Biol. 2016 Apr 15;11(4):900-9. doi: 10.1021/acschembio.5b00647. Epub 2016 Jan 6. ACS Chem Biol. 2016. PMID: 26682473 Free PMC article.

6

Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1.

Maben Z, Arya R, Rane D, An WF, Metkar S, Hickey M, Bender S, Ali A, Nguyen TT, Evnouchidou I, Schilling R, Stratikos E, Golden J, Stern LJ. Maben Z, et al. Among authors: ali a. J Med Chem. 2020 Jan 9;63(1):103-121. doi: 10.1021/acs.jmedchem.9b00293. Epub 2019 Dec 30. J Med Chem. 2020. PMID: 31841350 Free PMC article.

7

Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir.

Timm J, Kosovrasti K, Henes M, Leidner F, Hou S, Ali A, Kurt Yilmaz N, Schiffer CA. Timm J, et al. Among authors: ali a. ACS Chem Biol. 2020 Feb 21;15(2):342-352. doi: 10.1021/acschembio.9b00675. Epub 2020 Jan 8. ACS Chem Biol. 2020. PMID: 31868341 Free PMC article.

8

Inhibiting HTLV-1 Protease: A Viable Antiviral Target.

Lockbaum GJ, Henes M, Talledge N, Rusere LN, Kosovrasti K, Nalivaika EA, Somasundaran M, Ali A, Mansky LM, Kurt Yilmaz N, Schiffer CA. Lockbaum GJ, et al. Among authors: ali a. ACS Chem Biol. 2021 Mar 19;16(3):529-538. doi: 10.1021/acschembio.0c00975. Epub 2021 Feb 23. ACS Chem Biol. 2021. PMID: 33619959 Free PMC article.

9

First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.

Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, Schiffer CA, Harris RS. Li M, et al. Among authors: ali a. ACS Chem Biol. 2012 Mar 16;7(3):506-17. doi: 10.1021/cb200440y. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22181350 Free PMC article.

10

Testing the substrate-envelope hypothesis with designed pairs of compounds.

Shen Y, Altman MD, Ali A, Nalam MN, Cao H, Rana TM, Schiffer CA, Tidor B. Shen Y, et al. Among authors: ali a. ACS Chem Biol. 2013 Nov 15;8(11):2433-41. doi: 10.1021/cb400468c. Epub 2013 Sep 26. ACS Chem Biol. 2013. PMID: 23952265 Free PMC article.

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