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Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities.
Zagórska A, Partyka A, Bucki A, Kołaczkowski M, Jastrzębska-Więsek M, Czopek A, Siwek A, Głuch-Lutwin M, Bednarski M, Bajda M, Jończyk J, Piska K, Koczurkiewicz P, Wesołowska A, Pawłowski M. Zagórska A, et al. Among authors: kolaczkowski m. Chem Biol Drug Des. 2019 Apr;93(4):511-521. doi: 10.1111/cbdd.13442. Epub 2018 Dec 4. Chem Biol Drug Des. 2019. PMID: 30422400
Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation.
Kostrzewa T, Wołosewicz K, Jamrozik M, Drzeżdżon J, Siemińska J, Jacewicz D, Górska-Ponikowska M, Kołaczkowski M, Łaźny R, Kuban-Jankowska A. Kostrzewa T, et al. Among authors: kolaczkowski m. Int J Mol Sci. 2021 Sep 26;22(19):10368. doi: 10.3390/ijms221910368. Int J Mol Sci. 2021. PMID: 34638706 Free PMC article.
Serotonin 5-HT6 Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity-Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease.
Więckowski K, Szałaj N, Gryzło B, Wichur T, Góral I, Sługocka E, Sniecikowska J, Latacz G, Siwek A, Godyń J, Bucki A, Kołaczkowski M, Więckowska A. Więckowski K, et al. Among authors: kolaczkowski m. Int J Mol Sci. 2022 Aug 21;23(16):9443. doi: 10.3390/ijms23169443. Int J Mol Sci. 2022. PMID: 36012707 Free PMC article.
2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators.
Marcinkowska M, Fajkis-Zajączkowska N, Szafrańska K, Jończyk J, Siwek A, Mordyl B, Karcz T, Latacz G, Kolaczkowski M. Marcinkowska M, et al. Among authors: kolaczkowski m. ACS Chem Neurosci. 2023 Mar 15;14(6):1166-1180. doi: 10.1021/acschemneuro.2c00800. Epub 2023 Feb 27. ACS Chem Neurosci. 2023. PMID: 36848624 Free PMC article.
Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation.
Chłoń-Rzepa G, Jankowska A, Ślusarczyk M, Świerczek A, Pociecha K, Wyska E, Bucki A, Gawalska A, Kołaczkowski M, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: kolaczkowski m. Eur J Med Chem. 2018 Feb 25;146:381-394. doi: 10.1016/j.ejmech.2018.01.068. Epub 2018 Feb 4. Eur J Med Chem. 2018. PMID: 29407965
Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells - The involvement of carbonyl reductase 1 inhibition.
Piska K, Koczurkiewicz P, Wnuk D, Karnas E, Bucki A, Wójcik-Pszczoła K, Jamrozik M, Michalik M, Kołaczkowski M, Pękala E. Piska K, et al. Among authors: kolaczkowski m. Chem Biol Interact. 2019 Feb 25;300:40-48. doi: 10.1016/j.cbi.2019.01.003. Epub 2019 Jan 3. Chem Biol Interact. 2019. PMID: 30611789
137 results