Spratt DE - Search Results

1

Exchange Broadening Underlies the Enhancement of IDE-Dependent Degradation of Insulin by Anionic Membranes.

Zheng Q, Lee B, Kebede MT, Ivancic VA, Kemeh MM, Brito HL, Spratt DE, Lazo ND. Zheng Q, et al. Among authors: spratt de. ACS Omega. 2022 Jul 7;7(28):24757-24765. doi: 10.1021/acsomega.2c02747. eCollection 2022 Jul 19. ACS Omega. 2022. PMID: 35874268 Free PMC article.

2

The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme.

Krasinski CA, Zheng Q, Ivancic VA, Spratt DE, Lazo ND. Krasinski CA, et al. Among authors: spratt de. ACS Chem Neurosci. 2018 Dec 19;9(12):2892-2897. doi: 10.1021/acschemneuro.8b00305. Epub 2018 Aug 3. ACS Chem Neurosci. 2018. PMID: 30067897 Free PMC article.

3

Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme.

Ivancic VA, Krasinski CA, Zheng Q, Meservier RJ, Spratt DE, Lazo ND. Ivancic VA, et al. Among authors: spratt de. Biosci Rep. 2018 Nov 7;38(6):BSR20181416. doi: 10.1042/BSR20181416. Print 2018 Dec 21. Biosci Rep. 2018. PMID: 30305381 Free PMC article.

4

Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42.

Krasinski CA, Ivancic VA, Zheng Q, Spratt DE, Lazo ND. Krasinski CA, et al. Among authors: spratt de. ACS Omega. 2018 Oct 31;3(10):13275-13282. doi: 10.1021/acsomega.8b01913. Epub 2018 Oct 16. ACS Omega. 2018. PMID: 30411033 Free PMC article.

5

Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme.

Zheng Q, Kebede MT, Lee B, Krasinski CA, Islam S, Wurfl LA, Kemeh MM, Ivancic VA, Jakobsche CE, Spratt DE, Lazo ND. Zheng Q, et al. Among authors: spratt de. Antioxidants (Basel). 2021 Aug 25;10(9):1342. doi: 10.3390/antiox10091342. Antioxidants (Basel). 2021. PMID: 34572974 Free PMC article.

6

An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity.

Beasley SA, Kellum CE, Orlomoski RJ, Idrizi F, Spratt DE. Beasley SA, et al. Among authors: spratt de. PLoS One. 2020 Jul 8;15(7):e0235925. doi: 10.1371/journal.pone.0235925. eCollection 2020. PLoS One. 2020. PMID: 32639967 Free PMC article.

7

Exploring the Roles of HERC2 and the NEDD4L HECT E3 Ubiquitin Ligase Subfamily in p53 Signaling and the DNA Damage Response.

Mathieu NA, Levin RH, Spratt DE. Mathieu NA, et al. Among authors: spratt de. Front Oncol. 2021 Mar 31;11:659049. doi: 10.3389/fonc.2021.659049. eCollection 2021. Front Oncol. 2021. PMID: 33869064 Free PMC article. Review.

8

Small-Molecule Gankyrin Inhibition as a Therapeutic Strategy for Breast and Lung Cancer.

Kanabar D, Goyal M, Kane EI, Chavan T, Kabir A, Wang X, Shukla S, Almasri J, Goswami S, Osman G, Kokolis M, Spratt DE, Gupta V, Muth A. Kanabar D, et al. Among authors: spratt de. J Med Chem. 2022 Jul 14;65(13):8975-8997. doi: 10.1021/acs.jmedchem.2c00190. Epub 2022 Jun 27. J Med Chem. 2022. PMID: 35758870 Free PMC article.

9

Structural Insights into Ankyrin Repeat-Containing Proteins and Their Influence in Ubiquitylation.

Kane EI, Spratt DE. Kane EI, et al. Among authors: spratt de. Int J Mol Sci. 2021 Jan 9;22(2):609. doi: 10.3390/ijms22020609. Int J Mol Sci. 2021. PMID: 33435370 Free PMC article. Review.

10

¹H, ¹³C, and ¹⁵N resonance assignments of the C-terminal lobe of the human HECT E3 ubiquitin ligase ITCH.

Beasley SA, Bardhi R, Spratt DE. Beasley SA, et al. Among authors: spratt de. Biomol NMR Assign. 2019 Apr;13(1):15-20. doi: 10.1007/s12104-018-9843-2. Epub 2018 Sep 18. Biomol NMR Assign. 2019. PMID: 30229450 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

472 results

Search Page