Saez-Rodriguez J - Search Results

1

Integrating knowledge and omics to decipher mechanisms via large-scale models of signaling networks.

Garrido-Rodriguez M, Zirngibl K, Ivanova O, Lobentanzer S, Saez-Rodriguez J. Garrido-Rodriguez M, et al. Mol Syst Biol. 2022 Jul;18(7):e11036. doi: 10.15252/msb.202211036. Mol Syst Biol. 2022. PMID: 35880747 Free PMC article. Review.

2

Reduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling.

Conzelmann H, Saez-Rodriguez J, Sauter T, Bullinger E, Allgöwer F, Gilles ED. Conzelmann H, et al. Syst Biol (Stevenage). 2004 Jun;1(1):159-69. doi: 10.1049/sb:20045011. Syst Biol (Stevenage). 2004. PMID: 17052126

3

Signaling networks in MS: a systems-based approach to developing new pharmacological therapies.

Kotelnikova E, Bernardo-Faura M, Silberberg G, Kiani NA, Messinis D, Melas IN, Artigas L, Schwartz E, Mazo I, Masso M, Alexopoulos LG, Mas JM, Olsson T, Tegner J, Martin R, Zamora A, Paul F, Saez-Rodriguez J, Villoslada P. Kotelnikova E, et al. Mult Scler. 2015 Feb;21(2):138-46. doi: 10.1177/1352458514543339. Epub 2014 Aug 11. Mult Scler. 2015. PMID: 25112814 Free article. Review.

4

Phosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeast.

Vaga S, Bernardo-Faura M, Cokelaer T, Maiolica A, Barnes CA, Gillet LC, Hegemann B, van Drogen F, Sharifian H, Klipp E, Peter M, Saez-Rodriguez J, Aebersold R. Vaga S, et al. Mol Syst Biol. 2014 Dec 9;10(12):767. doi: 10.15252/msb.20145112. Mol Syst Biol. 2014. PMID: 25492886 Free PMC article.

5

Modeling Signaling Networks to Advance New Cancer Therapies.

Saez-Rodriguez J, MacNamara A, Cook S. Saez-Rodriguez J, et al. Annu Rev Biomed Eng. 2015;17:143-63. doi: 10.1146/annurev-bioeng-071813-104927. Epub 2015 Aug 14. Annu Rev Biomed Eng. 2015. PMID: 26274601 Review.

6

Data-driven reverse engineering of signaling pathways using ensembles of dynamic models.

Henriques D, Villaverde AF, Rocha M, Saez-Rodriguez J, Banga JR. Henriques D, et al. PLoS Comput Biol. 2017 Feb 6;13(2):e1005379. doi: 10.1371/journal.pcbi.1005379. eCollection 2017 Feb. PLoS Comput Biol. 2017. PMID: 28166222 Free PMC article.

7

Phosphoproteomics-Based Profiling of Kinase Activities in Cancer Cells.

Wirbel J, Cutillas P, Saez-Rodriguez J. Wirbel J, et al. Methods Mol Biol. 2018;1711:103-132. doi: 10.1007/978-1-4939-7493-1_6. Methods Mol Biol. 2018. PMID: 29344887 Free PMC article.

8

Computational discovery of dynamic cell line specific Boolean networks from multiplex time-course data.

Razzaq M, Paulevé L, Siegel A, Saez-Rodriguez J, Bourdon J, Guziolowski C. Razzaq M, et al. PLoS Comput Biol. 2018 Oct 29;14(10):e1006538. doi: 10.1371/journal.pcbi.1006538. eCollection 2018 Oct. PLoS Comput Biol. 2018. PMID: 30372442 Free PMC article.

9

Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data.

Schäfer A, Gjerga E, Welford RW, Renz I, Lehembre F, Groenen PM, Saez-Rodriguez J, Aebersold R, Gstaiger M. Schäfer A, et al. Mol Syst Biol. 2019 Aug;15(8):e8828. doi: 10.15252/msb.20198828. Mol Syst Biol. 2019. PMID: 31464372 Free PMC article.

10

From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL.

Liu A, Trairatphisan P, Gjerga E, Didangelos A, Barratt J, Saez-Rodriguez J. Liu A, et al. NPJ Syst Biol Appl. 2019 Nov 11;5:40. doi: 10.1038/s41540-019-0118-z. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31728204 Free PMC article.

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