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Neutral endopeptidase (NEP) inhibitors - thiorphan, sialorphin, and its derivatives exert anti-proliferative activity towards colorectal cancer cells in vitro.
Mizerska-Kowalska M, Kreczko-Kurzawa J, Zdzisińska B, Czerwonka A, Sławińska-Brych A, Maćkiewicz Z, Nidzworski D, Kandefer-Szerszeń M. Mizerska-Kowalska M, et al. Among authors: zdzisinska b. Chem Biol Interact. 2019 Jul 1;307:105-115. doi: 10.1016/j.cbi.2019.04.033. Epub 2019 May 1. Chem Biol Interact. 2019. PMID: 31054283
Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production.
Sławińska-Brych A, Zdzisińska B, Czerwonka A, Mizerska-Kowalska M, Dmoszyńska-Graniczka M, Stepulak A, Gagoś M. Sławińska-Brych A, et al. Among authors: zdzisinska b. Biochim Biophys Acta Gen Subj. 2019 Nov;1863(11):129408. doi: 10.1016/j.bbagen.2019.08.001. Epub 2019 Aug 3. Biochim Biophys Acta Gen Subj. 2019. PMID: 31386885
Tropinone-Derived Alkaloids as Potent Anticancer Agents: Synthesis, Tyrosinase Inhibition, Mechanism of Action, DFT Calculation, and Molecular Docking Studies.
Piechowska K, Mizerska-Kowalska M, Zdzisińska B, Cytarska J, Baranowska-Łączkowska A, Jaroch K, Łuczykowski K, Płaziński W, Bojko B, Kruszewski S, Misiura K, Łączkowski KZ. Piechowska K, et al. Among authors: zdzisinska b. Int J Mol Sci. 2020 Nov 28;21(23):9050. doi: 10.3390/ijms21239050. Int J Mol Sci. 2020. PMID: 33260768 Free PMC article.
Alpha Ketoglutarate Exerts In Vitro Anti-Osteosarcoma Effects through Inhibition of Cell Proliferation, Induction of Apoptosis via the JNK and Caspase 9-Dependent Mechanism, and Suppression of TGF-β and VEGF Production and Metastatic Potential of Cells.
Kaławaj K, Sławińska-Brych A, Mizerska-Kowalska M, Żurek A, Bojarska-Junak A, Kandefer-Szerszeń M, Zdzisińska B. Kaławaj K, et al. Among authors: zdzisinska b. Int J Mol Sci. 2020 Dec 10;21(24):9406. doi: 10.3390/ijms21249406. Int J Mol Sci. 2020. PMID: 33321940 Free PMC article.
New Borane-Protected Derivatives of α-Aminophosphonous Acid as Anti-Osteosarcoma Agents: ADME Analysis and Molecular Modeling, In Vitro Studies on Anti-Cancer Activities, and NEP Inhibition as a Possible Mechanism of Anti-Proliferative Activity.
Mizerska-Kowalska M, Sowa S, Donarska B, Płaziński W, Sławińska-Brych A, Tomasik A, Ziarkowska A, Łączkowski KZ, Zdzisińska B. Mizerska-Kowalska M, et al. Among authors: zdzisinska b. Int J Mol Sci. 2022 Jun 16;23(12):6716. doi: 10.3390/ijms23126716. Int J Mol Sci. 2022. PMID: 35743158 Free PMC article.
49 results