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The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation.
Smith KJ, Minns D, McHugh BJ, Holloway RK, O'Connor R, Williams A, Melrose L, McPherson R, Miron VE, Davidson DJ, Gwyer Findlay E. Smith KJ, et al. Among authors: miron ve. PLoS Biol. 2022 Aug 26;20(8):e3001554. doi: 10.1371/journal.pbio.3001554. eCollection 2022 Aug. PLoS Biol. 2022. PMID: 36026478 Free PMC article.
Activin receptors regulate the oligodendrocyte lineage in health and disease.
Dillenburg A, Ireland G, Holloway RK, Davies CL, Evans FL, Swire M, Bechler ME, Soong D, Yuen TJ, Su GH, Becher JC, Smith C, Williams A, Miron VE. Dillenburg A, et al. Among authors: miron ve. Acta Neuropathol. 2018 Jun;135(6):887-906. doi: 10.1007/s00401-018-1813-3. Epub 2018 Feb 3. Acta Neuropathol. 2018. PMID: 29397421 Free PMC article.
Central nervous system regeneration is driven by microglia necroptosis and repopulation.
Lloyd AF, Davies CL, Holloway RK, Labrak Y, Ireland G, Carradori D, Dillenburg A, Borger E, Soong D, Richardson JC, Kuhlmann T, Williams A, Pollard JW, des Rieux A, Priller J, Miron VE. Lloyd AF, et al. Among authors: miron ve. Nat Neurosci. 2019 Jul;22(7):1046-1052. doi: 10.1038/s41593-019-0418-z. Epub 2019 Jun 10. Nat Neurosci. 2019. PMID: 31182869 Free PMC article.
Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.
Van Steenwinckel J, Schang AL, Krishnan ML, Degos V, Delahaye-Duriez A, Bokobza C, Csaba Z, Verdonk F, Montané A, Sigaut S, Hennebert O, Lebon S, Schwendimann L, Le Charpentier T, Hassan-Abdi R, Ball G, Aljabar P, Saxena A, Holloway RK, Birchmeier W, Baud O, Rowitch D, Miron V, Chretien F, Leconte C, Besson VC, Petretto EG, Edwards AD, Hagberg H, Soussi-Yanicostas N, Fleiss B, Gressens P. Van Steenwinckel J, et al. Brain. 2019 Dec 1;142(12):3806-3833. doi: 10.1093/brain/awz319. Brain. 2019. PMID: 31665242 Free PMC article.
Microglia regulate central nervous system myelin growth and integrity.
McNamara NB, Munro DAD, Bestard-Cuche N, Uyeda A, Bogie JFJ, Hoffmann A, Holloway RK, Molina-Gonzalez I, Askew KE, Mitchell S, Mungall W, Dodds M, Dittmayer C, Moss J, Rose J, Szymkowiak S, Amann L, McColl BW, Prinz M, Spires-Jones TL, Stenzel W, Horsburgh K, Hendriks JJA, Pridans C, Muramatsu R, Williams A, Priller J, Miron VE. McNamara NB, et al. Among authors: miron ve. Nature. 2023 Jan;613(7942):120-129. doi: 10.1038/s41586-022-05534-y. Epub 2022 Dec 14. Nature. 2023. PMID: 36517604 Free PMC article.
Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration.
Molina-Gonzalez I, Holloway RK, Jiwaji Z, Dando O, Kent SA, Emelianova K, Lloyd AF, Forbes LH, Mahmood A, Skripuletz T, Gudi V, Febery JA, Johnson JA, Fowler JH, Kuhlmann T, Williams A, Chandran S, Stangel M, Howden AJM, Hardingham GE, Miron VE. Molina-Gonzalez I, et al. Among authors: miron ve. Nat Commun. 2023 Jun 8;14(1):3372. doi: 10.1038/s41467-023-39046-8. Nat Commun. 2023. PMID: 37291151 Free PMC article.
60 results