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The Anticancer Effects of the Pro-Apoptotic Benzofuran-Isatin Conjugate (5a) Are Associated With p53 Upregulation and Enhancement of Conventional Chemotherapeutic Drug Efficiency in Colorectal Cancer Cell Lines.
Vaali-Mohammed MA, Abdulla MH, Matou-Nasri S, Eldehna WM, Meeramaideen M, Elkaeed EB, El-Watidy M, Alhassan NS, Alkhaya K, Al Obeed O. Vaali-Mohammed MA, et al. Among authors: elkaeed eb. Front Pharmacol. 2022 Aug 15;13:923398. doi: 10.3389/fphar.2022.923398. eCollection 2022. Front Pharmacol. 2022. PMID: 36046830 Free PMC article.
Development of novel isatin-nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing-bacteria.
Elsayed ZM, Eldehna WM, Abdel-Aziz MM, El Hassab MA, Elkaeed EB, Al-Warhi T, Abdel-Aziz HA, Abou-Seri SM, Mohammed ER. Elsayed ZM, et al. Among authors: elkaeed eb. J Enzyme Inhib Med Chem. 2021 Dec;36(1):384-393. doi: 10.1080/14756366.2020.1868450. J Enzyme Inhib Med Chem. 2021. PMID: 33406941 Free PMC article.
Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities.
Elbadawi MM, Eldehna WM, Nocentini A, Abo-Ashour MF, Elkaeed EB, Abdelgawad MA, Alharbi KS, Abdel-Aziz HA, Supuran CT, Gratteri P, Al-Sanea MM. Elbadawi MM, et al. Among authors: elkaeed eb. Eur J Med Chem. 2021 Jun 5;218:113360. doi: 10.1016/j.ejmech.2021.113360. Epub 2021 Mar 13. Eur J Med Chem. 2021. PMID: 33773285
Development of 3-methyl/3-(morpholinomethyl)benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells.
Al-Sanea MM, Al-Ansary GH, Elsayed ZM, Maklad RM, Elkaeed EB, Abdelgawad MA, Bukhari SNA, Abdel-Aziz MM, Suliman H, Eldehna WM. Al-Sanea MM, et al. Among authors: elkaeed eb. J Enzyme Inhib Med Chem. 2021 Dec;36(1):987-999. doi: 10.1080/14756366.2021.1915302. J Enzyme Inhib Med Chem. 2021. PMID: 33985397 Free PMC article.
2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights.
Elbadawi MM, Eldehna WM, Abd El-Hafeez AA, Somaa WR, Albohy A, Al-Rashood ST, Agama KK, Elkaeed EB, Ghosh P, Pommier Y, Abe M. Elbadawi MM, et al. Among authors: elkaeed eb. J Enzyme Inhib Med Chem. 2022 Dec;37(1):349-372. doi: 10.1080/14756366.2021.2015344. J Enzyme Inhib Med Chem. 2022. PMID: 34923887 Free PMC article.
Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights.
Eldehna WM, Maklad RM, Almahli H, Al-Warhi T, Elkaeed EB, Abourehab MAS, Abdel-Aziz HA, El Kerdawy AM. Eldehna WM, et al. Among authors: elkaeed eb. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1227-1240. doi: 10.1080/14756366.2022.2062337. J Enzyme Inhib Med Chem. 2022. PMID: 35470754 Free PMC article.
146 results