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IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation.
Popli S, Chakravarty S, Fan S, Glanz A, Aras S, Nagy LE, Sen GC, Chakravarti R, Chattopadhyay S. Popli S, et al. Among authors: nagy le. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2121385119. doi: 10.1073/pnas.2121385119. Epub 2022 Sep 6. Proc Natl Acad Sci U S A. 2022. PMID: 36067309 Free PMC article.
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis.
Osborn LJ, Schultz K, Massey W, DeLucia B, Choucair I, Varadharajan V, Banerjee R, Fung K, Horak AJ 3rd, Orabi D, Nemet I, Nagy LE, Wang Z, Allende DS, Willard BB, Sangwan N, Hajjar AM, McDonald C, Ahern PP, Hazen SL, Brown JM, Claesen J. Osborn LJ, et al. Among authors: nagy le. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2202934119. doi: 10.1073/pnas.2202934119. Epub 2022 Nov 23. Proc Natl Acad Sci U S A. 2022. PMID: 36417437 Free PMC article.
TH17 cells promote CNS inflammation by sensing danger signals via Mincle.
Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, Zhang CJ, Zhao J, Zhang R, Liu C, Kang Z, Bermel RA, Dubyak G, Abbott DW, Xiao TS, Nagy LE, Li X. Zhang Q, et al. Among authors: nagy le. Nat Commun. 2022 May 3;13(1):2406. doi: 10.1038/s41467-022-30174-1. Nat Commun. 2022. PMID: 35504893 Free PMC article.
209 results