Luthra PM - Search Results

1

A_2A R mediated modulation in IP₃ levels altering the [Ca²⁺]_i through cAMP-dependent PKA signalling pathway.

Barodia SK, Sophronea T, Luthra PM. Barodia SK, et al. Among authors: luthra pm. Biochim Biophys Acta Gen Subj. 2022 Dec;1866(12):130242. doi: 10.1016/j.bbagen.2022.130242. Epub 2022 Sep 6. Biochim Biophys Acta Gen Subj. 2022. PMID: 36084905

2

Antagonism of haloperidol-induced swim impairment in L-dopa and caffeine treated mice: a pre-clinical model to study Parkinson's disease.

Luthra PM, Barodia SK, Raghubir R. Luthra PM, et al. J Neurosci Methods. 2009 Apr 15;178(2):284-90. doi: 10.1016/j.jneumeth.2008.12.019. Epub 2008 Dec 25. J Neurosci Methods. 2009. PMID: 19146880

3

In silico study of naphtha [1, 2-d] thiazol-2-amine with adenosine A 2A receptor and its role in antagonism of haloperidol-induced motor impairments in mice.

Luthra PM, Prakash A, Barodia SK, Kumari R, Mishra CB, Kumar JB. Luthra PM, et al. Neurosci Lett. 2009 Oct 9;463(3):215-8. doi: 10.1016/j.neulet.2009.07.085. Epub 2009 Aug 3. Neurosci Lett. 2009. PMID: 19654038

4

Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists.

Luthra PM, Mishra CB, Jha PK, Barodia SK. Luthra PM, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1214-8. doi: 10.1016/j.bmcl.2009.11.133. Epub 2009 Dec 4. Bioorg Med Chem Lett. 2010. PMID: 20018509

5

Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists.

Mishra CB, Barodia SK, Prakash A, Senthil Kumar JB, Luthra PM. Mishra CB, et al. Among authors: luthra pm. Bioorg Med Chem. 2010 Apr 1;18(7):2491-500. doi: 10.1016/j.bmc.2010.02.048. Epub 2010 Mar 1. Bioorg Med Chem. 2010. PMID: 20303771

6

Novel 8-(furan-2-yl)-3-benzyl thiazolo [5,4-e][1,2,4] triazolo [1,5-c] pyrimidine-2(3H)-thione as selective adenosine A(2A) receptor antagonist.

Barodia SK, Mishra CB, Prakash A, Senthil Kumar JB, Kumari N, Luthra PM. Barodia SK, et al. Among authors: luthra pm. Neurosci Lett. 2011 Jan 13;488(1):1-5. doi: 10.1016/j.neulet.2010.08.006. Epub 2010 Aug 11. Neurosci Lett. 2011. PMID: 20708066

7

Design and synthesis of benzo[d]thiazol-2-yl-methyl-4-(substituted)-piperazine-1-carbothioamide as novel neuronal nitric oxide inhibitors and evaluation of their neuroprotecting effect in 6-OHDA-induced unilateral lesioned rat model of Parkinson's disease.

Agrawal S, Kumari R, Sophronea T, Kumari N, Luthra PM. Agrawal S, et al. Among authors: luthra pm. Biomed Pharmacother. 2022 Dec;156:113838. doi: 10.1016/j.biopha.2022.113838. Epub 2022 Oct 20. Biomed Pharmacother. 2022. PMID: 36274466 Free article.

8

A_2AR antagonists triggered the AMPK/m-TOR autophagic pathway to reverse the calcium-dependent cell damage in 6-OHDA induced model of PD.

Sophronea T, Agrawal S, Kumari N, Mishra J, Walecha V, Luthra PM. Sophronea T, et al. Among authors: luthra pm. Neurochem Int. 2024 Jun 15:105793. doi: 10.1016/j.neuint.2024.105793. Online ahead of print. Neurochem Int. 2024. PMID: 38880232

9

Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists.

Mishra CB, Sharma D, Prakash A, Kumari N, Kumar N, Luthra PM. Mishra CB, et al. Among authors: luthra pm. Bioorg Med Chem. 2013 Oct 1;21(19):6077-83. doi: 10.1016/j.bmc.2013.07.005. Epub 2013 Jul 13. Bioorg Med Chem. 2013. PMID: 23953686

10

Pharmacological assessments of potent A_2A receptor antagonist IDPU (1-(7-imino-3-propyl-2,3-dihydrothiazolo[4,5-d]pyrimidin-6(7H)-yl)urea) in rodent model of haloperidol induced Parkinson like symptoms.

Kumari N, Agrawal S, Luthra PM. Kumari N, et al. Among authors: luthra pm. Neurosci Lett. 2017 Apr 24;647:53-60. doi: 10.1016/j.neulet.2017.03.033. Epub 2017 Mar 20. Neurosci Lett. 2017. PMID: 28336342

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